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A Guide on How to Administer Erelzi

4 min read

According to the European Medicines Agency, Erelzi (etanercept) is a biosimilar drug used to treat various inflammatory conditions like rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. The medication is administered via a subcutaneous injection, and proper technique is crucial for its safety and effectiveness. This guide provides detailed steps on how to administer Erelzi.

Quick Summary

A comprehensive guide to administering Erelzi using either the Sensoready pen or the prefilled syringe. It details the steps for preparation, proper injection technique, storage requirements, and what to do after the injection is complete.

Key Points

  • Receive Proper Training: Always get trained by a healthcare professional before attempting to self-administer Erelzi to ensure correct technique.

  • Prepare Correctly: Wash your hands, gather supplies, and let the medication warm to room temperature for 15-30 minutes before injecting.

  • Inspect the Solution: Visually check the liquid for clarity and color; do not inject if it is cloudy, discolored, or contains large particles.

  • Rotate Injection Sites: To minimize irritation, rotate between the abdomen, thighs, and outer upper arms, avoiding areas that are bruised, red, or hard.

  • Use Sharps Container: Immediately dispose of the used pen or syringe in a puncture-resistant sharps container to prevent injury.

  • Handle with Care: Do not shake the medication and protect it from light and extreme temperatures.

In This Article

Before You Begin: Essential Preparation

Proper preparation is the cornerstone of a safe and effective Erelzi injection. Before touching your medication, always wash your hands thoroughly with soap and water to prevent infection. Gather all necessary supplies: your Erelzi Sensoready pen or prefilled syringe, an alcohol swab, a cotton ball or gauze, and a sharps disposal container. Always ensure you have received training from a healthcare provider before attempting to self-administer.

Step-by-Step Preparation

  • Remove from Refrigeration: Take the carton containing your Erelzi injection out of the refrigerator and place it on a clean, flat surface.
  • Warm to Room Temperature: Allow the medication to sit for 15 to 30 minutes to reach room temperature. Injecting cold medication can cause discomfort. Do not remove the needle cap or pen cap during this time, and never use a microwave or hot water to speed up the process.
  • Inspect the Medication: Check the liquid through the viewing window of the pen or syringe. The solution should be clear to slightly yellowish and may contain tiny white protein particles. Do not use the medication if it is cloudy, discolored, or contains large lumps, flakes, or colored particles.
  • Select and Clean the Injection Site: Acceptable injection sites include the front of the thighs, the lower abdomen (at least 2 inches away from the navel), and the outer upper arms. Use a fresh alcohol swab to clean the injection site, wiping in a circular motion, and let the area dry completely before injecting.

Choosing an Injection Site

To prevent discomfort and irritation, it is vital to rotate your injection site with each dose. Keep a log or map of previous injection sites to ensure you don't inject into the same spot. Never inject into skin that is tender, bruised, red, hard, thick, scaly, scarred, or marked with stretch marks.

How to Administer Erelzi with the Sensoready Pen

The Sensoready pen is a user-friendly autoinjector designed for ease of use. Follow these steps carefully:

  1. Remove the Cap: Pull the cap straight off the pen only when you are ready to inject. Do not twist it. If you don't inject within a certain timeframe (usually 5 minutes), you may need to discard the pen.
  2. Position the Pen: Hold the pen firmly and place it at a 90-degree angle against the cleaned injection site.
  3. Start the Injection: Press the pen down firmly on the skin until you hear the first click. A green indicator will appear in the window.
  4. Wait for the Second Click: Continue holding the pen in place until you hear a second click, which indicates the injection is complete. The green indicator in the window will stop moving. The injection may take a specific duration to complete (up to 15 seconds).
  5. Remove the Pen: Lift the pen straight up from the skin. The needle will automatically retract into the pen for safety.

How to Administer Erelzi with the Prefilled Syringe

For those using the prefilled syringe, the technique is slightly different:

  1. Uncap the Needle: Remove the needle cap carefully just before the injection. Do not touch the needle.
  2. Pinch the Skin: Gently pinch a fold of skin at the cleaned injection site. This creates a firm surface for the injection.
  3. Insert the Needle: Hold the syringe like a pen and insert the needle at a 45-degree angle (or as instructed by your healthcare provider) into the pinched skin.
  4. Inject the Medication: Push the plunger slowly and steadily until all the liquid has been injected.
  5. Release the Skin and Withdraw: Release the pinched skin and carefully withdraw the needle at the same angle it was inserted.

Comparison: Sensoready Pen vs. Prefilled Syringe

Feature Sensoready Pen Prefilled Syringe
Design Autoinjector with covered needle and automatic retraction. Standard syringe with a removable needle cap.
Ease of Use Often preferred for its automatic function and audible clicks, which confirm correct administration. Requires more manual dexterity and comfort with handling a needle.
Injection Speed Automated delivery, which typically takes a specific duration. Manual, allowing the user to control the speed of injection.
Technique Push and click, holding until the second click. Pinch skin, insert needle manually, and push plunger.
Needle Guard Built-in safety guard retracts automatically after injection to prevent needle-stick injuries. Needle must be disposed of carefully in a sharps container after use.

After the Injection

Once the injection is complete, follow these steps to ensure safety and proper care:

  • Handle the Injection Site: A small amount of bleeding may occur. Apply a cotton ball or gauze to the injection site and press gently for 10 seconds. Do not rub the injection site.
  • Dispose of Supplies: Immediately place the used Sensoready pen or prefilled syringe into a puncture-resistant sharps disposal container. Never reuse a pen or syringe, and do not put the cap back on a used needle.
  • Monitor for Side Effects: Common side effects include mild injection site reactions (redness, swelling, pain) and symptoms like a stuffy nose or sore throat. Serious side effects are rare, but contact your doctor immediately if you experience signs of infection, serious allergic reactions, or nervous system problems.

Conclusion

Administering Erelzi correctly is a crucial part of managing your treatment plan, whether using the Sensoready pen or the prefilled syringe. By following the preparation steps, using the proper injection technique, and handling post-injection care responsibly, you can ensure a safe and effective treatment. Always consult with your healthcare provider for training and to address any concerns regarding your medication. For additional information, you can also refer to the official prescribing information on the U.S. Food and Drug Administration (FDA) website.

Frequently Asked Questions

You should inject Erelzi into the fatty tissue of the front of your thighs, the lower abdomen (avoiding the area 2 inches around the navel), or the outer upper arms. Always rotate your injection site with each dose.

Allow your Erelzi pen or syringe to warm up to room temperature for 15 to 30 minutes before injection. Injecting cold medication can cause discomfort. Do not speed up the process with heat.

If you miss a dose, inject it as soon as you remember, then continue with your regular dosing schedule as advised by your healthcare provider. Do not take a double dose to make up for the missed one. If you are unsure, contact your doctor or pharmacist for advice.

A normal Erelzi solution is clear to slightly yellowish and may contain small, white protein particles. You should not use the medication if it is cloudy, discolored, or contains large clumps or flakes.

No, both the Sensoready pen and the prefilled syringe are single-use devices. After completing the injection, immediately dispose of the device in a designated sharps container.

The Sensoready pen should make two clicks—one to start the injection and a second one when it's complete. If you don't hear the second click or see the green indicator, you may not have received a full dose. Contact your doctor immediately if this happens.

Store Erelzi in the refrigerator at 2°C to 8°C (36°F to 46°F) in its original carton to protect it from light. Do not freeze the medication. It can be stored at room temperature for a single period of up to 28 days.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.