Skip to content

Are tetanus injections safe?

4 min read

Since the 1940s, tetanus vaccines have reduced reported cases in the U.S. by over 95% and deaths by over 99% [1.9.3]. So, are tetanus injections safe enough to justify their widespread use? The evidence points to yes for the vast majority of people.

Quick Summary

Tetanus injections are overwhelmingly safe and effective. Most side effects are mild and temporary, such as soreness. Severe reactions are very rare, and the benefits of preventing a fatal disease far outweigh the potential risks.

Key Points

  • Overwhelmingly Safe: Tetanus vaccines are very safe, and severe reactions are rare [1.2.1, 1.3.3].

  • Mild Side Effects are Common: Most side effects are minor and temporary, like soreness at the injection site, low-grade fever, and body aches [1.3.2].

  • Disease is Worse Than a Shot: The risks from contracting tetanus, a potentially fatal disease, are far greater than the risks from the vaccine [1.4.1].

  • Protection for All Ages: Different vaccine formulations (DTaP, Tdap, Td) are recommended for different age groups, from infants to seniors [1.5.1].

  • Crucial for Pregnancy: Getting the Tdap vaccine during each pregnancy is safe and helps protect the newborn from whooping cough [1.8.1, 1.8.3].

  • Boosters are Necessary: Protection from tetanus vaccines decreases over time, so adults need a Td or Tdap booster shot every 10 years [1.2.3, 1.10.2].

  • Know the Contraindications: The main reason to not get a tetanus shot is a prior severe allergic reaction (anaphylaxis) to the vaccine [1.6.2].

In This Article

Understanding Tetanus: A Preventable Threat

Tetanus, often called lockjaw, is a severe and potentially fatal disease caused by the bacterium Clostridium tetani [1.4.1]. These bacteria are found in the environment, including in soil, dust, and manure [1.4.1]. They can enter the body through breaks in the skin, such as cuts, puncture wounds, or burns [1.5.1]. The infection causes painful muscle contractions, particularly in the jaw and neck, which can interfere with the ability to breathe and ultimately lead to death [1.10.3]. Before the widespread use of the vaccine, there were 500-600 tetanus cases reported annually in the United States. Since the mid-1970s, that number has dropped to an average of about 29 cases per year, demonstrating the vaccine's incredible success [1.9.2].

Types of Tetanus Vaccines

There isn't a vaccine for just tetanus. It is always given as a combination vaccine. The specific type you receive depends on your age and vaccination history [1.5.1, 1.5.4].

  • DTaP (Diphtheria, Tetanus, and acellular Pertussis): This vaccine is for infants and children under the age of 7. It's part of the standard childhood vaccination series, administered in five doses at 2, 4, 6, and 15-18 months, and again at 4-6 years [1.7.3].
  • Tdap (Tetanus, Diphtheria, and acellular Pertussis): This is a booster shot for adolescents and adults. It contains a full dose of the tetanus vaccine but reduced doses of diphtheria and pertussis toxoids compared to DTaP [1.5.4]. It is typically first given between ages 11 and 12 [1.5.5]. It's also recommended during each pregnancy to protect the newborn from whooping cough [1.8.1].
  • Td (Tetanus and Diphtheria): This vaccine is given as a booster every 10 years to adults to maintain protection against tetanus and diphtheria [1.10.2]. It can be used interchangeably with Tdap for the 10-year booster after an adult has received at least one Tdap dose [1.7.3].

Comparison of Common Tetanus Vaccines

Vaccine Target Age Group Protects Against Primary Use
DTaP Infants and children under 7 [1.5.1] Diphtheria, Tetanus, Pertussis Primary childhood vaccination series [1.7.3]
Tdap Adolescents and Adults (11+) [1.5.1] Diphtheria, Tetanus, Pertussis Adolescent booster, adult booster, pregnancy [1.5.5]
Td Adolescents and Adults (7+) [1.5.1] Diphtheria, Tetanus 10-year booster shot, wound management [1.5.1, 1.10.2]

Are Tetanus Injections Safe? Evaluating Side Effects and Risks

Tetanus vaccines are considered very safe and effective [1.2.1]. Like any medicine, they can have side effects, but the vast majority are mild and resolve on their own within a few days [1.2.3].

Common, Mild Side Effects

The most frequent side effects are localized reactions at the injection site [1.3.2, 1.3.4]:

  • Pain, redness, or swelling where the shot was given
  • Mild fever and chills
  • Headache and body aches
  • Fatigue
  • Nausea, vomiting, or diarrhea
  • Loss of appetite

These reactions are a normal sign that your body is building protection. You can often manage these symptoms with over-the-counter pain relievers and a cool compress on the injection site [1.11.2].

Rare but Serious Side Effects

Serious reactions to tetanus vaccines are very rare [1.3.3]. The Centers for Disease Control and Prevention (CDC) states that the risk of problems from the disease is much greater than from the vaccine [1.3.5, 1.4.1]. Severe reactions can include:

  • Severe Allergic Reaction (Anaphylaxis): Signs include hives, swelling of the face and throat, and difficulty breathing [1.3.4]. This reaction is estimated to occur in less than one in a million doses and requires immediate medical attention [1.3.5, 1.11.1].
  • High Fever: A fever over 105°F is very rare, occurring in about 1 in 16,000 children who receive DTaP [1.3.2].
  • Seizures: These are also rare, affecting about 1 in 14,000 children after a DTaP shot, and are often related to fever [1.3.2].
  • Guillain-Barré Syndrome (GBS): This is a rare disorder where the body's immune system damages nerves. Studies have found no association between Tdap vaccination and GBS [1.2.1, 1.8.4]. However, a history of GBS within 6 weeks of a previous tetanus vaccine is a precaution [1.6.1].

Who Should (and Shouldn't) Get a Tetanus Shot?

Vaccination is recommended for people of all ages [1.2.3]. However, there are some specific situations where the vaccine should be avoided or postponed.

Contraindications and Precautions

A contraindication is a reason a person should not receive a vaccine. The primary contraindication for a tetanus shot is a history of a severe allergic reaction (anaphylaxis) to a previous dose or a vaccine component [1.6.2, 1.6.5]. Another contraindication for the pertussis component in DTaP/Tdap is having developed encephalopathy (like a coma or prolonged seizures) not attributable to another cause within 7 days of a previous dose [1.6.2].

Precautions are conditions where the risks and benefits should be weighed carefully. You should talk to your doctor if you have [1.6.1, 1.6.5]:

  • A history of Guillain-Barré Syndrome (GBS).
  • A history of severe swelling or pain after a previous tetanus or diphtheria vaccine.
  • A progressive or unstable neurologic disorder.
  • A moderate or severe acute illness (vaccination should be postponed until you recover).

Special Recommendations

  • Pregnancy: The Tdap vaccine is recommended during the third trimester of every pregnancy, ideally between 27 and 36 weeks [1.8.1, 1.8.3]. This is very safe and helps pass protective antibodies to the baby, protecting them from whooping cough in the first few months of life [1.8.1].
  • Wound Care: If you get a severe or dirty cut or burn, you may need a tetanus booster. A shot is recommended if it's been more than 5 years since your last one for a dirty wound, or more than 10 years for a clean one [1.5.2, 1.10.4].

Conclusion: The Verdict on Safety

The consensus among major health organizations like the CDC is clear: tetanus injections are safe and highly effective [1.2.1, 1.2.3]. The discomfort of a sore arm for a day or two is a minor inconvenience compared to the devastating effects of the tetanus disease itself. Decades of data show that the benefits of vaccination in preventing a life-threatening illness far outweigh the very small risks of a serious adverse reaction [1.4.1]. Staying up-to-date with your tetanus boosters—a shot every 10 years for most adults—is a critical and safe part of lifelong health maintenance [1.10.2].

For more detailed information, you can visit the CDC's page on Tetanus Vaccination.

Frequently Asked Questions

A tetanus booster shot provides protection for about 10 years. The CDC recommends that adults get a Td or Tdap booster every 10 years to maintain immunity [1.10.1, 1.10.2].

The most common side effects are mild and include pain, redness, or swelling at the injection site, a low fever, headache, and tiredness. These usually go away on their own within a few days [1.3.2, 1.3.4].

Yes, it is highly recommended. The CDC advises all pregnant women to get a Tdap vaccine during the third trimester of each pregnancy to pass protective antibodies to the baby [1.8.1].

Both vaccines protect against tetanus and diphtheria. However, Tdap also includes protection against pertussis (whooping cough). Tdap is recommended as a one-time dose for adults who have never had it, during pregnancy, and for wound care, while Td is typically used for the routine 10-year booster [1.5.1, 1.5.4].

If you have a deep or dirty wound, you should get a tetanus booster if it has been more than five years since your last shot. For a clean, minor wound, a booster is recommended if it's been over 10 years [1.5.2, 1.10.4]. You should get the shot as soon as possible, ideally within 48 hours [1.10.4].

Anyone who has had a previous life-threatening allergic reaction (anaphylaxis) to a tetanus vaccine or any of its components should not get another dose. You should also consult a doctor if you have certain neurological conditions or had Guillain-Barré syndrome after a prior dose [1.6.2, 1.6.5].

No, you cannot get tetanus from the vaccine. The shot uses a toxoid, which is an inactivated form of the tetanus toxin, so it cannot cause the disease [1.3.3, 1.4.1].

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10
  11. 11
  12. 12
  13. 13
  14. 14
  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
  20. 20
  21. 21
  22. 22
  23. 23

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.