Can I use latanoprost to grow my eyelashes?: Understanding Off-Label Use and Risks

October 10, 2025 •

3 min read

First reported in 1997, the prostaglandin analog latanoprost was observed to cause a side effect of excessive eyelash growth, or hypertrichosis. While primarily an FDA-approved eye drop for treating glaucoma and ocular hypertension, many people now wonder, "Can I use latanoprost to grow my eyelashes?" despite the significant safety concerns associated with its off-label cosmetic use.

Quick Summary

Latanoprost, a glaucoma medication, can stimulate eyelash growth as an off-label side effect. This use is not FDA-approved and carries risks like permanent iris color change, eyelid darkening, and irritation. There are safer, approved alternatives for cosmetic eyelash enhancement.

Key Points

Not FDA-Approved for Cosmetic Use: Latanoprost is a prescription medication approved for treating glaucoma, and its use for cosmetic eyelash enhancement is considered an unapproved, off-label application.
Permanent Iris Color Change Risk: One of the most serious side effects is the potential for irreversible brown pigmentation of the iris, a risk that increases with long-term use and is more pronounced in light-colored eyes.
Eyelash Growth is a Side Effect: Latanoprost works by prolonging the natural eyelash growth cycle (anagen phase), leading to longer, thicker, and darker lashes, a recognized side effect in glaucoma patients.
Approved Alternative Exists: For those seeking safe, proven eyelash growth, the FDA-approved alternative is bimatoprost (Latisse), which is specifically formulated and tested for this cosmetic purpose.
Requires Medical Supervision: The use of latanoprost, particularly for off-label purposes, should only occur under the strict supervision of a healthcare professional due to the risk of significant ocular side effects.
Reversible Eyelid Darkening: While iris color changes are permanent, the darkening of the skin on and around the eyelids caused by the drug is often reversible upon discontinuation.
Ocular Irritation and Other Risks: Common side effects include eye redness, itching, and irritation, with rarer but more serious risks like macular edema also reported.

What is Latanoprost?

Latanoprost is a synthetic prostaglandin analog primarily prescribed to treat glaucoma and ocular hypertension. These conditions involve high pressure inside the eye, which can harm the optic nerve and lead to vision loss. Latanoprost works by increasing fluid drainage from the eye, thus lowering pressure. Brand names include Xalatan and Xelpros.

A notable side effect observed during its use has been increased eyelash growth, length, thickness, and darkness. This led to interest in using such compounds for cosmetic lash enhancement.

How Does Latanoprost Promote Eyelash Growth?

Latanoprost influences the hair growth cycle. It can activate resting hair follicles to start growing sooner and extend the active growth phase, resulting in longer lashes. It also causes follicles to enlarge, leading to thicker and more numerous lashes, and increases melanin, making them darker. These effects develop gradually over weeks to months.

Potential Risks and Side Effects of Off-Label Use

Using latanoprost for cosmetic eyelash growth off-label is not FDA-approved and carries significant risks. Common side effects include permanent iris color changes, eyelid skin darkening, and ocular irritation. More serious, though less common, issues like swelling of the retina can occur. Unwanted hair growth in other areas and the risk of eye infections are also concerns.

Latanoprost vs. Bimatoprost (Latisse)

For those considering cosmetic eyelash enhancement, it's important to compare latanoprost with bimatoprost, sold as Latisse. For a detailed comparison of features including primary indication, FDA approval status, efficacy, application method, side effect profile, cost, and necessary medical supervision, please refer to {Link: Pharmaceutical Journal https://pharmaceutical-journal.com/article/ld/latanoprost-as-a-cosmetic-for-eyelashes}.

Is Using Latanoprost for Eyelash Growth a Good Idea?

Generally, using latanoprost off-label for cosmetic lash growth is not recommended due to the significant risks, especially permanent iris color change. FDA-approved alternatives like Latisse (bimatoprost) offer a safer, regulated option.

Latanoprost is a prescription drug for a medical condition; obtaining or using it without a prescription for cosmetic purposes is dangerous.
Always consult an eye care professional before using any eye treatment. They can assess risks and suggest safe options.
Prioritize eye health over temporary cosmetic benefits.

Alternatives to Latanoprost for Eyelash Enhancement

Safer options exist for those seeking longer, fuller lashes:

FDA-Approved Bimatoprost (Latisse): The most effective and safest prescription for cosmetic enhancement.
Peptide-Based Lash Serums: Over-the-counter serums condition and strengthen lashes without the ocular risks of prostaglandin analogs.
Natural Remedies: Some use castor oil for conditioning, though scientific evidence is limited.
Cosmetic Products: Mascaras and primers can enhance lash appearance.
Proper Lash Care: Gentle cleaning and moisturizing prevent breakage.

Conclusion

While latanoprost can cause eyelash growth as a side effect, its off-label use for cosmetic purposes carries significant, potentially permanent risks like iris discoloration. It is not FDA-approved for this use. A safer, approved alternative is bimatoprost (Latisse), which is specifically intended and regulated for cosmetic eyelash enhancement. Consulting a healthcare professional is crucial before using any medication off-label. The risks of using latanoprost to grow my eyelashes for cosmetic reasons typically outweigh the benefits.

Sources

Note: The use of latanoprost for eyelash enhancement is not supported by regulatory bodies like the FDA due to safety concerns. This information is for educational purposes only and is not medical advice. Consult a healthcare provider before using any medication for off-label purposes.

Frequently Asked Questions

While using a prescribed medication for an unapproved purpose is not illegal, it is considered off-label use and is not endorsed by regulatory bodies like the FDA for cosmetic purposes. Doctors typically do not prescribe it for this reason due to the associated risks.

Noticeable eyelash growth with latanoprost typically appears after several weeks, with significant results usually visible after about two to four months of consistent application.

Yes, latanoprost can cause permanent changes to iris pigmentation, particularly in individuals with light-colored eyes. This involves an increase in melanin and will not reverse after stopping the medication.

Common side effects include eyelid skin darkening (which is usually reversible), eye irritation, redness, itching, and potential thickening or darkening of the eyelashes.

Latisse (bimatoprost) is the FDA-approved product specifically for cosmetic eyelash growth and is considered the safer option. Its formulation and application method are designed to minimize risks compared to the off-label use of latanoprost.

The eyelash growth effects are temporary. After discontinuing the drug, your eyelashes will gradually return to their previous appearance and growth cycle over time. However, any iris color change is likely to be permanent.

No. Latanoprost often contains a preservative that can be absorbed by contact lenses. It is recommended to remove contact lenses before application and wait at least 15 minutes before reinserting them.