What is Latisse and How Does It Work?
Latisse is the brand name for a prescription ophthalmic solution containing the active ingredient bimatoprost 0.03% [1.2.4]. It is the first and only treatment approved by the U.S. Food and Drug Administration (FDA) for treating hypotrichosis, the condition of having inadequate or not enough eyelashes [1.4.1]. By applying Latisse to the base of the upper eyelashes daily, users can experience longer, thicker, and darker eyelashes [1.2.3].
The active ingredient, bimatoprost, is a synthetic prostaglandin analog [1.7.5]. Its exact mechanism for promoting eyelash growth is not fully understood. However, researchers believe it works by increasing the duration of the anagen (growth) phase of the hair cycle and increasing the number of hairs in this phase [1.4.1, 1.7.4]. Bimatoprost was originally used in a medication called Lumigan to treat glaucoma (high intraocular pressure). During those treatments, patients incidentally discovered their eyelashes were growing longer and fuller, which led to the development and FDA approval of Latisse for cosmetic use in 2008 [1.6.2, 1.7.4].
The Connection: Can Latisse Cause Itchy Eyes?
Yes, one of the most frequently reported side effects of using Latisse is itchy eyes, medically known as ocular pruritus [1.4.5, 1.8.4]. Clinical studies and prescribing information consistently list eye itching and redness as the most common adverse reactions, affecting approximately 4% of users [1.4.1, 1.9.3].
This itching can occur immediately after application but often subsides. For many new users, the sensation is temporary and may last for only the first one to two weeks of use [1.4.3]. The irritation is not necessarily an allergic reaction and doesn't typically indicate harm to the eyes [1.4.3]. However, if the itching is persistent, severe, or accompanied by other symptoms like significant redness, swelling, or vision changes, it is crucial to consult a doctor [1.2.2, 1.8.4].
Several factors can contribute to the itching sensation:
- The Active Ingredient: Bimatoprost itself, as a prostaglandin analog, can cause inflammatory responses like redness and itching [1.7.3].
- The Preservative: Latisse contains benzalkonium chloride (BAK) as a preservative, which is known to cause eye irritation and dry eye symptoms in some individuals [1.5.1].
- Incorrect Application: Allowing the solution to run into the eye or using too much product can increase the likelihood of irritation [1.5.3]. It's important to apply only one drop per sterile applicator and blot away any excess [1.10.2].
How to Manage Itchy Eyes from Latisse
If you experience itchiness while using Latisse, several strategies can help manage the discomfort:
- Ensure Proper Application: Use only the sterile, single-use applicators provided. Apply a single drop to the applicator and carefully trace it along the base of the upper lash line. Do not apply it to the lower lid or directly into the eye [1.10.2].
- Be Patient: For many, the initial itching subsides after a couple of weeks as your body adjusts [1.4.3].
- Use Sparingly: Over-saturating the brush will not increase results but can increase the risk of side effects [1.2.2].
- Apply to a Clean Face: Remove all makeup and contact lenses before application. You can reinsert contact lenses 15 minutes after applying Latisse [1.6.2].
- Use a Cold Compress: A clean, cool washcloth placed over closed eyes can help soothe irritation [1.3.5].
- Consult Your Doctor: If itching is severe or persistent, speak with your healthcare provider. They may recommend lubricating eye drops (artificial tears) or suggest a temporary break from the product [1.2.2, 1.5.1].
Other Potential Side Effects and Warnings
While itchy eyes are common, it's important to be aware of other potential side effects:
- Eye Redness (Conjunctival Hyperemia): Occurs in under 4% of patients and often accompanies itching [1.4.5].
- Eyelid Skin Darkening (Hyperpigmentation): The skin where Latisse is applied may darken. This effect is usually reversible after discontinuing use [1.6.2, 1.8.2].
- Dry Eyes and Irritation: Feelings of dryness or burning can occur [1.5.5].
- Permanent Iris Color Change: Bimatoprost can cause the colored part of the eye (iris) to become more brown. This change is more common when the drug is dropped directly into the eye for glaucoma treatment but is a known, though infrequent, risk with Latisse. This change is likely to be permanent [1.6.4, 1.8.2].
- Hair Growth Outside Treatment Area: If the solution regularly trickles onto other skin areas, unwanted hair growth can occur. Always blot any excess solution [1.10.4].
Individuals with pre-existing eye conditions like uveitis or macular edema, or those using medications for elevated eye pressure, should use Latisse with caution and under the close supervision of an ophthalmologist [1.6.2, 1.10.5].
Comparison of Lash Serum Side Effects
Latisse stands apart from over-the-counter (OTC) lash serums because its active ingredient, bimatoprost, is FDA-approved for eyelash growth [1.7.4]. Many OTC serums use different, non-FDA-approved prostaglandin analogs like isopropyl cloprostenate, which carry similar risks of irritation and potential for more serious side effects like periorbital fat loss (a sunken-eye appearance) [1.7.1, 1.7.5].
| Feature | Latisse (Bimatoprost) | Over-the-Counter (OTC) Prostaglandin Serums | Peptide/Vitamin-Based Serums |
|---|---|---|---|
| Regulation | FDA-approved prescription [1.7.4] | Not FDA-approved for lash growth [1.7.5] | Cosmetic, not regulated as a drug |
| Primary Active Ingredient | Bimatoprost (Prostaglandin Analog) [1.4.1] | Isopropyl Cloprostenate or similar (Prostaglandin Analogs) [1.7.5] | Peptides, Biotin, Keratin |
| Common Side Effects | Itchy/red eyes, eyelid skin darkening [1.4.5] | Itchy/red eyes, irritation, potential for darkening [1.7.1] | Generally lower risk of irritation |
| Serious Potential Risks | Permanent iris color change (infrequent) [1.6.4] | Periorbital fat loss, iris color change [1.7.1] | Allergic reactions to specific ingredients |
Conclusion
So, can Latisse cause itchy eyes? The answer is a definitive yes. It is the most common side effect, affecting a small but significant percentage of users, particularly during the initial weeks of treatment [1.4.5]. This irritation is usually mild and manageable by following proper application techniques. While Latisse is a proven and effective treatment for enhancing eyelashes, it is a prescription medication with potential side effects that should be discussed with a healthcare professional [1.6.2]. Understanding the risks, from common itchiness to rare but permanent changes, allows users to make an informed decision and use the product safely and effectively.
For more information directly from the manufacturer, you can visit the official Latisse® Website.
