Skip to content

Can you quit finasteride cold turkey? What to expect when you stop.

3 min read

Within 14 days of stopping finasteride, levels of DHT—the hormone that causes hair loss—return to pre-treatment levels. This rapid hormonal shift is the most significant consequence to consider if you're asking, 'Can you quit finasteride cold turkey?'.

Quick Summary

Stopping finasteride abruptly does not cause acute withdrawal symptoms, but it triggers a swift hormonal rebound, leading to the gradual resumption of hair loss over several months.

Key Points

  • DHT Rebound: DHT levels return to baseline within two weeks of stopping finasteride, causing the gradual reversal of hair loss benefits over several months.

  • No Acute Withdrawal: Stopping finasteride cold turkey does not cause acute withdrawal symptoms because the drug does not act on neurotransmitters in the same way as other medications.

  • Hair Loss Resumes: All hair gained or maintained while on the medication will likely be lost within 6-12 months after discontinuation.

  • Side Effects Usually Subside: Any temporary side effects experienced while on finasteride typically resolve within weeks of stopping the medication.

  • Risk of Post-Finasteride Syndrome: A rare but serious condition, PFS involves persistent sexual, mental, and physical side effects after quitting finasteride.

  • Consult a Doctor: It is essential to speak with a healthcare provider before stopping finasteride to discuss the implications and consider alternative treatment options.

In This Article

What Happens When You Quit Finasteride Cold Turkey?

Stopping finasteride cold turkey is generally not associated with acute withdrawal symptoms. Finasteride works by inhibiting the enzyme that converts testosterone into DHT. When you stop taking the medication, this inhibition ceases, and the drug is eliminated from your system relatively quickly due to its short half-life. Within about two weeks, your DHT levels return to pre-treatment levels.

The main consequence of discontinuing finasteride is the reversal of its effects on hair growth. The hair that was saved or regrown while on the medication will once again be subject to the hormonal changes that cause male pattern baldness. Therefore, the long-term impact on hair loss is the same whether you stop abruptly or taper off; some individuals choose to taper for psychological reasons, but there's no medical benefit in preventing hair loss resumption.

The Long-Term Consequences: Resuming Hair Loss

The most significant long-term effect of stopping finasteride is the return of male pattern baldness. Studies indicate that within 6 to 12 months after stopping, hair count typically returns to pre-treatment levels. This reversal is gradual, starting as DHT levels rebound and hair follicles begin to shrink again. For those taking finasteride for benign prostatic hyperplasia (BPH), discontinuing will lead to a return of prostate volume and BPH symptoms over several months.

Side Effects After Quitting: A Note on Post-Finasteride Syndrome (PFS)

Most people who experienced side effects while on finasteride, such as sexual issues, find that these resolve within a few weeks of stopping the medication. However, there is a rare but serious concern known as Post-Finasteride Syndrome (PFS). PFS is characterized by persistent sexual, physical, and neurological side effects that continue for at least three months after stopping treatment.

PFS symptoms can be wide-ranging and severe. The U.S. FDA has updated finasteride labeling to include information on persistent side effects. Potential symptoms may include:

  • Sexual symptoms: Persistent loss of libido, erectile dysfunction, and genital anesthesia.
  • Neurological symptoms: Depression, anxiety, and cognitive impairment.
  • Physical symptoms: Gynecomastia, muscle pain, and chronic fatigue.

If you experience persistent symptoms months after stopping, it is vital to consult a healthcare provider. While there is no standard treatment for PFS, symptoms can be managed, and research is ongoing.

Cold Turkey vs. Tapering: Which Is Better?

Feature Quitting Cold Turkey Tapering Off Gradually
Hormonal Rebound DHT levels return to baseline within 2 weeks. DHT levels also return to baseline, just at a slower rate.
Hair Loss Resumption Begins within weeks, visible hair loss 3-6 months later. Begins within weeks, visible hair loss 3-6 months later; no difference in final outcome.
Side Effect Resolution For most, temporary side effects resolve within weeks. Temporary side effects still resolve, but over a longer timeframe.
Risk of PFS Low but potential risk; no evidence suggests cold turkey increases this risk. Low but potential risk; no evidence suggests tapering decreases this risk.
Psychological Impact May cause anxiety due to sudden change. Provides a smoother psychological transition for some individuals.

Alternatives and Managing Future Hair Loss

If you stop finasteride and wish to continue managing hair loss, several other treatment options are available. Discussing these alternatives with a healthcare professional is crucial.

  • Minoxidil: A topical treatment that can stimulate hair growth.
  • Topical Finasteride: A localized version that may have fewer systemic side effects.
  • Hair Transplants: A more permanent surgical option.
  • Other Therapies: Options like PRP therapy and LLLT can also help promote hair growth.

Conclusion

In summary, quitting finasteride cold turkey is generally safe in terms of acute withdrawal symptoms. However, it will lead to the reversal of hair growth benefits as DHT levels normalize. While most side effects subside quickly, Post-Finasteride Syndrome (PFS) is a rare but serious concern. The method of stopping does not affect the long-term outcome regarding hair loss reversal. Always consult your doctor before stopping finasteride to discuss your situation, potential risks, and alternative treatments.

Learn more about finasteride's pharmacokinetics on the NCBI Bookshelf.

Frequently Asked Questions

If you quit finasteride, your hair loss will likely resume. Within 6 to 12 months, your hair count will typically return to where it was before you started the treatment, and the natural balding process will continue.

For finasteride, tapering off does not prevent hair loss from resuming. Since the drug's effects on DHT levels cease once it's out of your system, the final outcome concerning hair loss will be the same regardless of whether you stop abruptly or gradually.

For most people, any side effects like sexual dysfunction resolve within a few weeks of stopping the medication as hormone levels normalize. In rare cases of Post-Finasteride Syndrome (PFS), symptoms can persist for months or longer.

PFS is a term used to describe a rare condition where individuals report persistent sexual, neurological, and physical side effects for at least three months after stopping finasteride. It is a controversial but recognized condition that requires medical attention.

Yes, you can restart finasteride. Restarting the medication can halt further hair loss, but it will take several months to see new improvements, and results may not be as robust as the first time.

Yes, alternatives such as topical minoxidil, Platelet-Rich Plasma (PRP) therapy, or a hair transplant can be considered. It is best to discuss these options with your doctor.

Yes, it is always recommended to consult a healthcare provider before making any changes to your medication. They can provide guidance, help monitor for any side effects, and discuss alternative options.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.