Category: Adverse drug effects

The U.S. Food and Drug Administration (FDA) has issued a Black Box Warning for metoclopramide due to the risk of serious movement disorders. Understanding **what are serious side effects of metoclopramide** is vital for patient safety, as prolonged use can lead to potentially irreversible conditions like tardive dyskinesia.

According to data from the OpenVigil database, over 2,400 medications were identified as having the potential to induce supraventricular tachycardia over a period of 19 years. Understanding which drugs can trigger tachycardia is critical for both patients and healthcare providers to manage cardiovascular risks effectively.

Clinical studies and case reports confirm that the antifungal posaconazole is associated with an increased risk of hypokalemia, or low blood potassium levels. This occurs due to its inhibitory effects on specific adrenal steroid-producing enzymes, leading to a condition known as pseudohyperaldosteronism. Awareness and monitoring are critical for managing this potential adverse effect during treatment.

Fluoroquinolone antibiotics carry a black box warning from the FDA for their potential to increase the risk of tendonitis and tendon rupture. For many individuals, understanding **what drugs cause tendonitis** is a critical piece of information that can help prevent serious, long-term musculoskeletal damage from commonly prescribed medications.

According to the FDA, fluoroquinolone antibiotics are associated with an increased risk of tendinitis and tendon rupture in all age groups. While this risk is rare, it highlights the importance of understanding which drug may be associated with tendon injuries, as several classes of medications can contribute to tendon toxicity.

According to a 2020 meta-analysis of patients with multidrug-resistant tuberculosis (MDR-TB), 64% discontinued linezolid due to peripheral neuropathy. This serious adverse effect is primarily linked to the antibiotic's interference with mitochondrial protein synthesis, which is crucial for nerve cell function.

According to estimates, corticosteroid-induced osteonecrosis alone accounts for over 10% of the half-million total joint replacements performed annually in the U.S. Determining what medication most commonly causes osteonecrosis is complex, as it depends on the specific drug class and the affected part of the skeleton, with bisphosphonates and corticosteroids being the two primary culprits.