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Category: Anesthesiology

Explore our medication guides and pharmacology articles within this category.

What precautions should be taken during spinal anesthesia?

4 min read
The failure rate of spinal anesthesia can be as high as 17% [1.6.5]. Understanding **what precautions should be taken during spinal anesthesia** is crucial for patient safety, involving meticulous steps before, during, and after the procedure to mitigate risks and ensure effective outcomes.

A Pharmacological Guide: How is Hypotension Treated During Surgery?

5 min read
Intraoperative hypotension (IOH), defined in many settings as a mean arterial pressure (MAP) below 65 mmHg, is a common occurrence affecting a significant number of surgical patients. Timely and appropriate treatment is vital, as untreated IOH is strongly linked to a higher risk of postoperative complications, including acute kidney injury and myocardial injury. Understanding **How is hypotension treated during surgery?** is a cornerstone of modern anesthetic management aimed at maximizing patient safety.

Is a nerve block considered general anesthesia?

5 min read
Over 70% of patients undergoing orthopedic upper limb surgery report moderate to high postoperative pain, a challenge that different anesthesia methods address in unique ways [1.2.5]. Fundamentally, **is a nerve block considered general anesthesia?** No, they are distinct forms of anesthesia [1.2.1].

Which local anesthetic drug has the highest cardiotoxicity?

4 min read
Of all local anesthetics, bupivacaine is associated with the highest incidence of cardiac toxicity and is among the most challenging to treat in cases of systemic toxicity [1.2.1, 1.2.3, 1.2.6]. This article explores which local anesthetic drug has the highest cardiotoxicity and why.

Is bupivacaine or lidocaine more cardiotoxic? A comparative analysis

4 min read
Pharmacological studies and clinical evidence consistently demonstrate that bupivacaine is significantly more cardiotoxic than lidocaine, with its higher potency and different binding kinetics on cardiac sodium channels contributing to its increased risk. The distinction between these two commonly used local anesthetics is critical for anesthesiologists and other healthcare providers to manage local anesthetic systemic toxicity (LAST) effectively.

Fact vs. Fiction: Does Your Heart Stop Beating Under General Anesthesia?

4 min read
Each year, millions of people in the United States undergo noncardiac surgery, with about one-third having existing cardiac disease or major risk factors [1.6.5]. A common fear is, **does your heart stop beating under general anesthesia?** The answer is no, your heart continues to beat throughout the procedure [1.2.3].