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Category: Cell biology

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What is nls peptide? Unpacking Nuclear Localization Signals

4 min read
First identified in the Simian Virus 40 (SV40) large T-antigen, the nls peptide is a short amino acid sequence that functions as a critical cellular postal code, directing proteins and other molecules from the cytoplasm into the cell's nucleus. This active transport process is essential for many fundamental cellular processes, including DNA replication, transcription, and gene expression.