Category: Chronic pain

The global prevalence of Complex Regional Pain Syndrome (CRPS) is estimated to be between 5.5 and 26.2 per 100,000 people annually [1.5.1]. Understanding what painkillers are used for CRPS is key to managing this debilitating neuropathic pain condition.

Affecting approximately 25-30% of individuals with diabetes, painful diabetic neuropathy is a common and challenging complication. While **amitriptyline is used for diabetes**-related nerve pain, it is not prescribed to treat the underlying condition of diabetes itself. This article clarifies the drug's specific role, its mechanism of action, and important considerations for diabetic patients.

According to the National Institute on Drug Abuse, millions of people misused prescription pain relievers in the past year, highlighting the need for careful consideration of medications like Belbuca. For patients seeking alternatives for pain management, understanding **what is Belbuca comparable to** is crucial for making informed treatment decisions.

Chronic NSAID use is associated with thousands of hospitalizations and fatalities each year, particularly among older adults. This raises a critical question for many: **Can NSAIDs cause permanent damage?**

According to the Centers for Disease Control and Prevention (CDC), over 54 million U.S. adults have been diagnosed with some form of arthritis. Finding the best pain reliever for arthritis is a highly personalized process, as the most effective treatment varies significantly depending on the type and severity of the condition, as well as individual health factors.

While most muscle relaxers are intended only for short-term treatment of acute muscle spasms, some formulations and types are prescribed for daily use to manage chronic conditions. Navigating whether there is a muscle relaxer that can be taken daily requires understanding the specific medical need and potential risks involved.

Population-based studies indicate that up to 15% of adults experience symptoms of temporomandibular joint (TMJ) disorders, often resulting in significant chronic pain. For many patients, addressing this persistent discomfort leads to the common question: "Is amitriptyline good for TMJ pain?" This article explores the role of low-dose amitriptyline as an off-label treatment option for chronic TMJ-related pain.

Fibromyalgia affects between 2% and 8% of the global population, leading many to seek alternative treatment options when standard therapies fall short. In recent years, low-dose naltrexone (LDN) has emerged as a topic of great interest, sparking questions about whether naltrexone helps fibromyalgia and for whom this off-label approach might be effective.

In August 2025, the U.S. Food and Drug Administration (FDA) approved Tonmya (sublingual cyclobenzaprine), the first new medication for fibromyalgia in over 15 years, offering renewed hope for millions affected by this chronic condition. This development marks a significant advancement in pharmacological treatment options, specifically targeting the non-restorative sleep that often accompanies the widespread pain of fibromyalgia.

Originally approved for major depressive disorder in 2004, Cymbalta (duloxetine) is a versatile serotonin-norepinephrine reuptake inhibitor (SNRI) that addresses a wide range of mental and physical conditions. It is a unique medication because it effectively treats both mental health disorders and chronic pain states.