Category: Drug side effects

According to a 2023 press release regarding FDA approval for a drug reversing pharmacologically induced mydriasis, over 100 million thorough eye examinations involving dilating drops are performed in the United States each year. This common procedure, which intentionally causes mydriasis, highlights the significant role that various medications and substances play in affecting pupil size. Beyond clinical settings, a wide array of prescription, over-the-counter, and recreational drugs can also lead to dilated pupils.

In studies using isolated rat mast cells, atenolol was shown not to liberate histamine, suggesting it does not directly increase histamine levels. However, the relationship between beta-blockers like atenolol and allergic responses is complex, involving potential impacts on the body’s overall reaction to histamine, especially in severe allergic episodes. This article explores the pharmacological evidence to clarify how atenolol affects histamine and related allergic issues.

Atropine, an anticholinergic medication, is known to inhibit sweat gland activity, a side effect that can lead to an increase in body temperature, or hyperthermia. The question, **Does atropine increase temperature?**, is particularly relevant for vulnerable patients like infants and those in hot environments, where this effect can become dangerous.

Fatalities have occurred, although rarely, due to severe reactions to sulfonamides like acetazolamide [1.2.7]. Understanding 'what is the most severe effect of acetazolamide?' involves recognizing several life-threatening conditions, including blood disorders and severe skin reactions [1.3.2, 1.2.7].

Lupron (leuprolide) is a synthetic hormone used to treat conditions like prostate cancer, endometriosis, and central precocious puberty [1.7.6]. While effective, a key question for patients is: **Can Lupron cause a cough?** The answer is yes, this is a recognized side effect [1.2.2].

While commonly used to treat high blood pressure, amlodipine has a reported incidence of causing a rash in a small percentage of users, ranging from uncommon (0.1%-1%) to very rare occurrences. This side effect, along with other potential skin reactions, necessitates awareness among patients and healthcare providers.

Up to 3.5% of the global population experiences depression, with many requiring medication where certain antidepressants can cause side effects like dilated pupils. This guide explores **what drugs can cause dilated pupils** by interfering with the autonomic nervous system.

Clinical studies from the mid-20th century established a clear connection between the use of potent miotic agents and the development of lens opacities. This finding raised significant concern within the ophthalmology community, prompting research into the precise mechanisms that explain why miotics cause cataracts.

While intravenous acyclovir has been associated with severe nephrotoxicity in some cases, the risk with oral administration is lower. Therefore, the question, "Can acyclovir cause urinary problems?", warrants a closer look at the different forms of the drug and associated risk factors.

In 2023, the combination of amoxicillin and clavulanate potassium (Augmentin) was the second-most commonly prescribed antibiotic in the U.S., accounting for 10.28% of all antibiotic prescriptions [1.9.3]. This widespread use leads to important safety questions, such as: **Can Augmentin cause chest pain?**