Category: Drug withdrawal

According to the Merck Manual, one of the classic physical signs of opioid withdrawal is mydriasis, or pupil dilation. The seemingly simple question of what opioid causes mydriasis has a complex answer that depends heavily on context—whether it is an acute effect, a withdrawal symptom, or observed in different species.

Suddenly stopping an antipsychotic like ziprasidone (Geodon) is strongly discouraged and can cause a host of unpleasant and potentially severe withdrawal symptoms, known as discontinuation syndrome. Proper tapering under medical supervision is critical for a safe and successful outcome.