Category: Fitness

Clinical trials reveal that significant weight loss with GLP-1 agonists like semaglutide often involves losing lean body mass, including muscle. So, what does semaglutide do to muscle? The medication's primary effect is indirect, driven by appetite suppression, but proper exercise and nutrition can help mitigate muscle reduction.

Studies have consistently shown that for individuals with clinically low testosterone levels, supplementation can lead to notable increases in lean body mass and strength when combined with exercise. Understanding **what is the best testosterone to take for muscle growth** depends heavily on your medical status, legal restrictions, and health goals, differentiating between medically supervised therapy and recreational use.

For decades, creatine has been one of the most studied and safest performance-enhancing supplements, but what is the biggest side effect of creatine? The most consistently documented initial effect is an increase in body weight due to water retention within muscle cells, which often occurs during a loading phase.

Despite online speculation, L-carnitine is not linked to muscle wasting; in fact, clinical research indicates it may help protect against it. This is particularly evident in studies involving older adults and individuals with certain health conditions, where L-carnitine has been shown to help preserve lean body mass.

Agmatine is a naturally occurring compound produced in the body from the amino acid L-arginine. Given their close metabolic relationship, many athletes and fitness enthusiasts wonder: **Can you take arginine and agmatine together** for enhanced workout benefits? The answer, according to supplement manufacturers and some scientific inquiry, is that they can be effectively combined, offering synergistic effects for athletic performance.

Recent research from the University of New South Wales found that adding creatine to a weightlifting regimen did not build muscle faster for a group of resistance-trained adults. This adds to a growing body of evidence questioning why is creatine not worth it for many individuals seeking fitness benefits.

A 2015 study in the *International Journal of Food and Nutritional Science* found no adverse effects on blood pressure during the creatine loading phase in healthy males. However, the question remains: can creatine cause high blood pressure, especially for individuals with pre-existing conditions and those sensitive to temporary fluid retention?

While speculation regarding celebrity health choices is common, there is no publicly available definitive information confirming whether **Jason Statham uses TRT** (Testosterone Replacement Therapy). The action star is known for his intense fitness regimen and commitment to maintaining a peak physique well into his fifties.

According to numerous clinical studies, finasteride has not been shown to have a direct negative impact on muscle mass or strength. While finasteride alters hormone levels, particularly by inhibiting dihydrotestosterone (DHT), the primary driver for muscle anabolism—testosterone—remains sufficient for growth.

While generally well-tolerated, some individuals experience digestive issues, but is creatine a laxative? Recent studies indicate that while not a true laxative, high doses can lead to side effects like diarrhea, affecting over half of participants in one study who took 10 grams in a single dose.