What is the 4-2-1 rule for maintenance fluids?
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4 min read
The 4-2-1 rule is a widely used mnemonic in clinical practice for estimating intravenous (IV) fluid requirements, particularly for pediatric patients. First derived from the Holliday-Segar method based on caloric expenditure, understanding what is the 4-2-1 rule for maintenance fluids is crucial for managing hydration in hospitalized individuals.