Yes, Is Abilify Metabolized by Cytochrome P450? Exploring Its Metabolic Pathways and Genetic Influences
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5 min read
Aripiprazole, the active ingredient in the atypical antipsychotic Abilify, is extensively metabolized by the hepatic cytochrome P450 (CYP) enzyme system. This critical metabolic process is largely driven by two key enzymes, CYP2D6 and CYP3A4, which convert the drug into its active and inactive forms. Understanding these metabolic pathways is essential for managing therapeutic outcomes, potential drug-drug interactions, and addressing genetic variations in patients.
