Understanding Which Liver Enzyme Is Affected by Statins and Why It Matters
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4 min read
Statins, the most commonly prescribed class of cholesterol-lowering drugs, primarily inhibit HMG-CoA reductase, the key enzyme in the liver's cholesterol synthesis pathway. While this is their main mechanism, concern often arises about which liver enzyme is affected by statins when monitoring for potential liver side effects, most notably serum aminotransferases like ALT and AST.