Category: Histamine intolerance

Affecting an estimated 1-3% of the population, histamine intolerance can cause a wide range of symptoms, including significant digestive distress. This has led many to question what antacids are used for histamine intolerance, with H2 blockers being a key part of the answer for managing related gastric symptoms.

It's estimated that up to 20% of the population takes a medication that can decrease diamine oxidase (DAO) activity, the enzyme responsible for breaking down histamine. This makes understanding what medications make histamine intolerance worse a critical part of symptom management. This pharmacological guide will outline the key drug classes to be aware of and how they can interfere with histamine metabolism.