Category: Local anesthetics

While local anesthetic systemic toxicity (LAST) is a rare but life-threatening complication, with an estimated occurrence of 7.5 to 20 per 10,000 peripheral nerve blocks, it can lead to cardiotoxicity. This article examines the critical question: Does lidocaine cause cardiotoxicity, exploring the conditions under which this risk arises and how it is managed safely?

While largely replaced in modern dentistry, Novocaine (procaine) and other local anesthetics can, in rare cases, trigger a severe blood disorder called methemoglobinemia. This life-threatening condition reduces the blood's ability to carry oxygen and is one of the answers to the question, 'What is the rare condition in Novocaine?'.

With a history dating back to the 1930s, tetracaine is a long-standing tool in medical practice. So, what class of drug is tetracaine? It is an ester-type local anesthetic used to block nerve signals and induce temporary numbness for a variety of medical procedures.

Based on relative potency values, tetracaine is considered more potent than lidocaine, with ratios cited as 10 for tetracaine versus 4 for lidocaine. The question, 'Is tetracaine stronger than lidocaine?', requires an examination of factors beyond simple potency, including onset time, duration, and specific application methods.

Approximately 1% of the population may experience an allergic reaction to local anesthetics, with the risk being significantly higher for ester-based drugs. The key to understanding this difference lies in the basic chemical structure that determines **what drugs are ester and amide**, influencing their metabolism, longevity, and potential for adverse effects.

According to a study published in *Anesthesiology*, the choice between local anesthetics is highly dependent on clinical goals. When considering **which is better, lidocaine or bupivacaine**, healthcare professionals must weigh the trade-offs between rapid onset and long-lasting effects.

Prilocaine is a versatile local anesthetic of the amino amide type, used extensively in medical and dental fields to provide temporary numbness [1.3.3, 1.9.4]. What is the drug prilocaine used for? It is primarily employed to prevent pain during dental procedures and minor skin surgeries [1.10.4, 1.11.2].

Originally hailed as a safer and less toxic alternative to cocaine, Novicane, the brand name for the drug procaine, was the first synthetic injectable anesthetic. Its development in 1905 revolutionized pain management in medical and dental procedures, although its widespread use has since been replaced by more modern agents.

As a potent and fast-acting local anesthetic, tetracaine has been used for decades to provide temporary numbness before medical, dental, and minor surgical procedures. When asking **what is the use of tetracaine?**, one must consider its various formulations and targeted applications across different parts of the body.

Anethaine is a brand name for the local anesthetic tetracaine hydrochloride [1.3.2]. A highly effective anesthetic, it provides rapid, temporary numbness essential for various medical procedures [1.2.1]. So, what is Anethaine used for in clinical practice? It's a critical agent for ensuring patient comfort during short procedures in ophthalmology, dentistry, and more.