Category: Longevity

The global anti-aging market, valued at $52.5 billion in 2018, is projected to reach $83.2 billion by 2027, with many seeking advanced therapies like NAD+. But while NAD injections offer a rapid boost, many are asking: What's better than NAD injections?. The answer lies in a variety of alternatives, from targeted supplements to simple but powerful lifestyle changes.

While the idea of a universal anti-aging pill remains science fiction, a 2024 interview with a prominent longevity researcher highlighted several FDA-approved drugs that have shown potential to reduce age-related mortality in humans. The broader scientific conversation often includes four highly-researched compounds: Rapamycin, Metformin, Nicotinamide Mononucleotide (NMN), and Resveratrol, raising the question: **What are the 4 drugs for longevity?**

Over 20 years ago, Russian research revealed a peptide that could extend the lifespan of animal cells in laboratory settings, sparking global interest in its anti-aging potential. This groundbreaking compound, known as **what is epitalon?**, is a synthetic tetrapeptide derived from the naturally occurring polypeptide epithalamin. It has since been the focus of extensive research into its effects on cellular longevity and systemic health.

The body’s natural production of coenzyme Q10 (CoQ10) begins to decline around age 20. A common question arises for those seeking to replenish their levels through supplementation: **How long should I take a CoQ10 supplement?** The answer is not one-size-fits-all, as the optimal duration depends heavily on individual health goals and physiological factors.

NMN is a key precursor to NAD+, a coenzyme vital for cellular energy and DNA repair that naturally declines with age. This decline has led to a rise in NMN supplementation for longevity, but a critical question remains: **Do I need to take NMN with TMG?**

According to some observational studies, diabetic individuals taking metformin have a reduced risk of age-related diseases, such as cardiovascular disease and certain cancers, potentially lowering all-cause mortality compared to non-diabetics. This has sparked significant interest in its broader effects, prompting the question: **does metformin make you feel younger**?

While rapamycin is FDA-approved primarily for suppressing the immune system in organ transplant patients, its potential to extend lifespan has been shown in various animal models, including mice. The question of whether healthy people can take rapamycin for longevity and anti-aging purposes is complex and remains controversial among medical professionals.

Rapamycin is an FDA-approved prescription drug, not an over-the-counter dietary supplement. While its potential for longevity has sparked significant interest, anyone asking, 'Is there a rapamycin supplement?' must understand its legal status and medical implications.

A computer modeling study identified withaferin A as a strong mimetic of rapamycin's gene expression patterns, yet no single supplement can perfectly replicate the potent, targeted effects of the prescription drug. For those interested in modulating the same longevity pathways, the question becomes: what is the closest supplement to rapamycin among the available natural options? This article explores the most promising candidates.

Over time, our bodies' levels of Nicotinamide Adenine Dinucleotide (NAD+) naturally decline, which can influence energy metabolism and cellular function. For those considering supplementation, a key question is: how quickly do you see results with NMN?, its precursor? The timeline for experiencing benefits is not instant and varies significantly from person to person.