Is Rituximab for Lupus? Understanding Its Off-Label Use and Clinical Evidence
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4 min read
While not officially approved for systemic lupus erythematosus (SLE) by the U.S. Food and Drug Administration (FDA), rituximab is used off-label for lupus, particularly in cases that have not responded to standard treatments. As a B-cell depleting agent, it targets and removes certain B cells that are overactive in autoimmune diseases like lupus, yet its role has yielded mixed results in formal clinical trials.
