Category: Medical research

Ivermectin is an FDA-approved medication used to treat parasitic infections [1.2.1]. Recently, its potential anti-inflammatory and immunomodulatory properties have prompted investigation into a compelling question: Can ivermectin help autoimmune disease?

Recent research has revealed that nicotine, the addictive component in tobacco, possesses anti-inflammatory properties, a seemingly paradoxical finding given smoking's well-documented destructive effects. This complex dual role is a subject of intense scientific scrutiny, with studies exploring its potential therapeutic applications in inflammatory diseases while acknowledging its overall toxicity and addictive nature.

The term 'delta' appears in many different contexts across science, but in pharmacology and medicine, it can refer to several distinct and critically important concepts. From endogenous receptors that modulate mood and pain to specific cannabinoid compounds and photosensitive agents for cancer, understanding the top 3 deltas provides a fascinating glimpse into diverse therapeutic strategies.

Autism Spectrum Disorder (ASD) affects approximately 2% of children in the United States [1.3.7]. Amidst ongoing research for effective therapies, a key question has emerged: Is leucovorin a surprising autism treatment for a specific subset of these children? [1.3.7, 1.7.4]

The global AI in drug discovery market was valued at $1.5 billion in 2023 and is projected to soar to $20.30 billion by 2030 [1.9.5]. This explosion in technology is accelerating the hunt for the answer to the question: **what is the next big drug?**

Globally, an estimated 20% of adults suffer from chronic pain, making the question 'What new painkiller could bring relief to millions?' a critical public health issue. A new, non-addictive class of drugs targeting peripheral nerves offers a promising answer.

Did you know that cotinine, the main metabolite of nicotine, has a half-life up to ten times longer than nicotine itself? [1.8.3] While famous as a biomarker for tobacco use, emerging science is now asking: what are the benefits of cotinine for brain health?

Over 600,000 individuals in the U.S. are affected by Ménière's disease, yet there are currently no FDA-approved medications specifically for this condition. The investigational oral drug **SPI-1005**, containing the compound **ebselen**, is a frontrunner in late-stage clinical trials, offering renewed hope for patients suffering from fluctuating hearing loss and episodic vertigo.

Trodusquemine (also known as MSI-1436) is a naturally occurring aminosterol originally discovered in the dogfish shark. This article explains how trodusquemine is administered within the context of its use in clinical research, as it is not approved for public use.

In 2023, nearly 80,000 people died from an opioid overdose in the United States [1.7.3]. This staggering statistic has fueled a decades-long search for a powerful new painkiller without addiction. That search has led to suzetrigine, a first-in-class medication offering hope for safer pain management [1.3.3, 1.4.5].