Category: Neuromuscular

Neostigmine, a classic drug developed in the 1930s, is clinically used to enhance the function of the cholinergic neuromuscular junction. This article clarifies its pharmacological classification by answering the question: Is neostigmine cholinergic or adrenergic?

Originally used as an arrow poison by indigenous South American tribes, the active compound, D-tubocurarine, was later adopted for clinical use to achieve muscle relaxation during surgery. Its ability to interfere with the neuromuscular junction made it a foundational substance in anesthesiology for decades.