Category: Obesity management

Clinical studies indicate that individuals using semaglutide alongside diet and exercise interventions can expect to lose an average of 5% to 10% of their body weight within the first three months of treatment. This provides a realistic benchmark for those beginning a medical weight management journey and wanting to know how much weight can you lose in 3 months with semaglutide.

According to a 2022 clinical trial, adults who stopped Wegovy after 68 weeks regained two-thirds of the weight they lost within a year, underscoring its long-term nature. This raises a key question for many patients considering this medication: **How long do most people stay on Wegovy for weight loss?**

According to a 2025 study in *JAMA Network Open*, a significant number of patients discontinue and reinitiate GLP-1 receptor agonist therapy, often requiring a strategy to safely jump start Wegovy again. Understanding the proper protocol is crucial to minimize side effects and get back on track with your weight management goals.

According to a May 2025 report from FAIR Health, more than 2% of U.S. adults took a GLP-1 medication for weight loss in 2024, highlighting the explosive demand for these treatments. Yet, determining **what is the number one weight loss drug in America?** is complex, as the answer depends on the criteria used to measure success, including prescription volume and clinical efficacy.

According to clinical trial data, gastrointestinal (GI) side effects like nausea and vomiting were among the most commonly reported issues for patients taking Zepbound. This fluid loss can lead to dehydration, making it a critical aspect of patient care. In this guide, we explore the question: **Does Zepbound cause dehydration**? We will also discuss how to manage this potential risk safely.

While there are no randomized controlled trials specifically evaluating GLP-1 medications for lipedema, patient reports and clinical observations suggest they can provide significant benefits for managing co-existing obesity and inflammation. Understanding which GLP-1 is best for lipedema depends on individual patient factors, including symptom profile, weight loss goals, and tolerance to side effects.