Category: Obesity treatment

In a head-to-head clinical trial, tirzepatide (Zepbound) demonstrated superior average weight loss compared to semaglutide (Wegovy), achieving a 20.2% reduction versus 13.7% over 72 weeks. This breakthrough introduces a strong contender to the popular GLP-1 medication, leading many to ask, **What is the new weight loss drug better than Wegovy?**

According to a 2013 study, a combination of phentermine and topiramate led to significantly greater weight loss than either drug alone, highlighting the effectiveness of combination therapy for weight management. Exploring what can I add to phentermine to lose weight requires careful medical evaluation, as options range from FDA-approved regimens to other potential, but riskier, combinations requiring strict medical oversight.

In a Phase 2 trial, pemvidutide helped patients achieve significant weight loss while demonstrating class-leading preservation of lean muscle mass. This investigational drug, known as pemvidutide, is a novel dual-agonist peptide with potential applications in obesity, metabolic dysfunction-associated steatohepatitis (MASH), and other metabolic diseases.