Category: Renal physiology

According to the FDA, lithium decreases the kidneys' reabsorption of sodium, a process that can lead to sodium depletion if not managed correctly. Understanding **what effect does lithium have on sodium** is critical for patients and healthcare providers to manage therapeutic levels and prevent severe toxicity.

Over 90% of drugs are eliminated from the body via renal excretion or hepatic metabolism, demonstrating their critical role in clearing substances. Understanding **what is the main route of drug elimination** is vital for determining drug dosing, predicting duration of action, and preventing toxicity.

More than half of all drugs are ultimately eliminated from the body by the kidneys via urine, serving as the main route of excretion for water-soluble compounds. This critical process of removing drugs and their metabolites is a cornerstone of pharmacology, influencing dosage and therapeutic outcomes. The key question is: Where are most drugs excreted?