Category: Sedatives

First synthesized in the early 20th century, barbiturates represent one of the older classes of sedative-hypnotic drugs [1.10.4]. The primary question for clinicians and patients today is: What is the therapeutic effect of butabarbital, and what are its modern applications?

Propiomazine, a phenothiazine derivative, is primarily known for its potent sedative properties, with its central mechanism of action involving antagonism at multiple receptor sites in the central nervous system. First approved in 1960, the drug's effects stem from its ability to block key neurotransmitter receptors, leading to its clinical use in treating insomnia and providing sedation.