Category: Sleep medicine

Melatonin is often marketed as a safe, natural sleep aid, but taking excessive amounts can be dangerous. A 2022 study by the CDC revealed a 530% increase in pediatric melatonin ingestions over a decade, highlighting serious risks. Here, we explore the alarming consequences of ingesting 1000 mg of melatonin.

The sleep cycle is composed of rapid eye movement (REM) and several non-REM stages [1.2.2]. This article answers the key question: what are REM medications and how do they pharmacologically influence this critical phase of sleep for therapeutic purposes?

Despite being one of the most frequently prescribed off-label sleep aids, major clinical guidelines recommend against using trazodone as a primary treatment for insomnia. This raises the critical question: **is trazodone good for sleep efficiency**, and what does the scientific evidence reveal about its true impact on sleep quality?

According to a recent 2025 study in the *British Journal of General Practice*, low-dose mirtazapine showed a clinically relevant reduction in insomnia severity at 6 weeks, unlike low-dose amitriptyline, which produced a smaller, non-clinically relevant effect. This critical finding helps clarify which is better for sleep, amitriptyline or mirtazapine, in the short term, but a deeper dive into their pharmacology, side effects, and long-term use is necessary for a complete picture.

According to the American Academy of Sleep Medicine, millions of adults experience chronic insomnia, driving continuous research for novel treatments. In 2025, while no single breakthrough drug received widespread U.S. FDA approval specifically for standalone insomnia, significant updates on pipeline candidates and new therapeutic approaches shed light on the future of sleep medicine. This raises the question: what is the new insomnia drug 2025?

According to the American Academy of Sleep Medicine, dual orexin receptor antagonists (DORAs) like Belsomra and Dayvigo offer a modern approach to treating insomnia by targeting wakefulness rather than inducing sedation. Deciding which is better, Belsomra or Dayvigo, for your specific sleep issues requires a detailed understanding of their subtle pharmacological differences, effectiveness, and safety profiles.

Affecting approximately 70 million Americans, insomnia can profoundly impact daily life, but low-dose medications like doxepin are an option for some. To answer the question of **what is the use of doxepin 10 mg tablet**, it is important to distinguish its application from higher-dose versions of the drug.

Approximately 8.2% of American adults report using a sleep aid at least four times in the last week, highlighting a common struggle with sleeplessness. This often leads to the question, **what is the best drug to induce sleep?** The answer is not one-size-fits-all, as the most effective and safest option depends on an individual's specific sleep issues and overall health.

According to clinical trials, daytime drowsiness is a frequently reported side effect by patients taking the sleep medication Ambien. When considering **what is the most common side effect of Ambien?**, understanding this residual sedation is critical for ensuring safety and managing daily activities.

Melatonin supplement sales more than doubled between 2017 and 2020, yet many healthcare providers remain cautious. The question, **why are doctors against melatonin?**, stems from significant concerns over inconsistent product quality, potential drug interactions, and unknown long-term effects on the body.