Category: Thermoregulation

Studies show that taking medications with strong anticholinergic properties is associated with a two-times greater risk of heat-related illness and death [1.2.1]. The critical question is, do anticholinergics increase body temperature and how significant is this risk?

Atropine, an anticholinergic medication, is known to inhibit sweat gland activity, a side effect that can lead to an increase in body temperature, or hyperthermia. The question, **Does atropine increase temperature?**, is particularly relevant for vulnerable patients like infants and those in hot environments, where this effect can become dangerous.

In a study of geriatric inpatients, those taking antipsychotic drugs (APDs) had a hypothermia incidence of 2.6%, compared to 1.3% in those not taking APDs [1.9.1]. Understanding **which drugs cause hypothermia** is critical for patient safety, especially in vulnerable populations.