Category: Transfusion medicine

According to established blood bank guidelines, the primary reason why should blood not be given with Ringer lactate is the significant risk of triggering coagulation due to a chemical incompatibility. This practice ensures patient safety by preventing potentially fatal clotting events within the intravenous line.

Approximately 72% of blood bank recommendations specify that Lactated Ringer's (LR) should be avoided when transfusing blood. This guideline is due to the potential for the LR's calcium to interact with the blood's anticoagulant, creating a risk of coagulation.

Standard blood bank recommendations specify that lactated Ringer's (LR) solution should be avoided when transfusing blood due to a theoretical risk of clotting. This long-standing guideline stems from the direct chemical incompatibility between the calcium in LR and the citrate anticoagulant used to preserve blood products.