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Decoding the Cost: How much is Zituvio in the US?

4 min read

The FDA approved Zituvio (sitagliptin) for Type 2 diabetes in October 2023, introducing a new option to the market. Understanding how much is Zituvio in the US is crucial, as costs can vary dramatically depending on insurance, pharmacy, and whether you use coupons or a patient assistance program.

Quick Summary

This guide breaks down Zituvio's pricing in the US, exploring the difference between brand-name retail costs and the significantly lower price of its authorized generic. It covers the impact of insurance and various savings opportunities.

Key Points

  • Retail Price is High: The average retail price for brand-name Zituvio without insurance can be over $500 for a 30-day supply.

  • Authorized Generic Available: An authorized generic of sitagliptin, identical to Zituvio, was launched by manufacturer Zydus, providing a much cheaper alternative.

  • Generic Cost as Low as $80: Certain direct-to-consumer pharmacies, like Marley Drug, offer the authorized generic for a cash price of $80 per month.

  • Discount Coupons are Effective: Websites like GoodRx and SingleCare can reduce the cash price for Zituvio and generic sitagliptin significantly.

  • Insurance Coverage Varies: Coverage depends on your specific plan's formulary; some plans may exclude brand-name Zituvio or require step therapy.

  • Patient Assistance is an Option: Patient assistance programs exist to help eligible, low-income, uninsured, or underinsured individuals access the medication for free or at a reduced cost.

In This Article

Understanding the Price of Zituvio (Sitagliptin)

Zituvio is a brand-name medication containing sitagliptin, a DPP-4 inhibitor used to treat Type 2 diabetes by helping the body produce more insulin after meals. While it offers an effective treatment option, the retail price can be high for those without adequate insurance. However, the cost landscape changed significantly with the availability of an authorized generic version shortly after its FDA approval, offering substantial savings.

The Brand-Name Retail Price

Without insurance, the cost of brand-name medications is typically prohibitive. For Zituvio, the retail price for a month's supply can be quite high, often exceeding several hundred dollars. This cost is the starting point before any discounts or insurance coverage are applied. Factors that influence this price include the pharmacy's retail markup and the specific dosage strength (25mg, 50mg, or 100mg), although the monthly price is often similar across dosages.

The More Affordable Authorized Generic

An authorized generic is a special type of generic that is identical to the brand-name drug but sold under a different label, and crucially, often at a much lower price. The manufacturer of Zituvio, Zydus Pharmaceuticals, also sells an authorized generic of sitagliptin. This has created an immediate, low-cost option for patients managing Type 2 diabetes. For example, some pharmacies, like Marley Drug, offer a monthly supply of the authorized generic sitagliptin for a cash price of around $80, bypassing traditional insurance and pharmacy benefit managers (PBMs) to pass savings directly to the patient.

The Impact of Insurance and Discount Cards

For those with health insurance, the out-of-pocket cost for Zituvio can range significantly based on the plan's formulary and tiering. Many commercial insurance plans, however, may place Zituvio on a non-preferred or even excluded tier, potentially requiring step therapy where a patient must first try a different medication. For Medicare Part D recipients, the copay can also vary, though programs exist to help with costs.

Prescription discount cards, such as those from GoodRx or SingleCare, offer another path to savings. These coupons can dramatically reduce the cash price for both the brand-name Zituvio and its authorized generic, making it more accessible for those without insurance or with high deductibles. The prices found via these cards are generally lower than the typical pharmacy retail price and can compete with the prices offered by direct-to-consumer pharmacies.

Strategies for Reducing Zituvio Costs

  • Discuss the Authorized Generic with Your Doctor: If you are prescribed brand-name Zituvio, ask your healthcare provider about prescribing the authorized generic sitagliptin. It's the same active ingredient and can lead to significant cost savings.
  • Compare Pharmacy Prices: Costs can differ widely between pharmacies. Use prescription price comparison websites or apps to check pricing at local pharmacies and find the best deal.
  • Utilize Pharmacy Direct Models: For patients paying cash, direct-to-consumer pharmacies like Marley Drug offer very low prices for the authorized generic by cutting out intermediaries.
  • Check Patient Assistance Programs: For uninsured or underinsured patients, Zydus may have patient assistance programs (PAPs) to help with the cost of Zituvio. Eligibility is typically based on income and requires filling out an application.

Comparison Table: Zituvio, Generic Sitagliptin, and Januvia

This table illustrates the varying costs for sitagliptin products, including the brand-name Zituvio, its authorized generic, and the original brand-name Januvia.

Product Status Estimated Retail Price (30 tablets) Estimated Discounted Price (30 tablets)
Zituvio (sitagliptin) Brand ~$525.09 ~$108.77 (GoodRx)
Generic Sitagliptin Authorized Generic ~$544 ~$80 (Marley Drug) or ~$102 (SingleCare)
Januvia (sitagliptin) Brand ~$777 ~$285 (SingleCare)

Note: Prices are estimates and subject to change based on pharmacy, location, and the specific coupon or discount program utilized. Generic sitagliptin is an authorized generic of Zituvio, not Januvia, but contains the same active ingredient.

Zituvio and the Broader Context of Diabetes Medication

It is essential to view Zituvio's cost within the context of other diabetes medications. Newer drug classes, such as GLP-1 receptor agonists (e.g., Ozempic, Mounjaro) and SGLT-2 inhibitors (e.g., Farxiga), are often very expensive, making the lower cost of generic sitagliptin a welcome development for many patients. The choice of medication should always be a collaborative decision between the patient and their healthcare provider, considering factors like effectiveness, potential side effects, and affordability. For more information on the FDA approval of Zituvio, see its official drug label at the FDA website.

Conclusion

For those asking how much is Zituvio in the US, the answer is that it varies significantly, with a clear distinction between the higher retail price of the brand-name drug and the much lower cost of its authorized generic counterpart. While brand-name costs without insurance are high, the introduction of an authorized generic by the manufacturer provides a highly affordable option for cash-paying patients. By exploring discount cards, patient assistance, and direct-to-consumer pharmacy models, patients with Type 2 diabetes can find ways to manage their medication costs effectively.

Frequently Asked Questions

The average retail price for 30 tablets of 100mg Zituvio can be upwards of $525.09, though this can vary by pharmacy.

Yes, an authorized generic version of sitagliptin, the active ingredient in Zituvio, is available from the manufacturer, Zydus Pharmaceuticals.

Using discount cards from services like GoodRx can reduce the price significantly. For example, a 30-tablet supply might cost around $108.77 or less with a coupon.

Coverage depends on your specific insurance plan. Some commercial and government plans may require step therapy or exclude Zituvio from their formulary, while others may cover it with a copay.

Alternatives include other DPP-4 inhibitors like Januvia (the original sitagliptin), Onglyza (saxagliptin), and Tradjenta (linagliptin), as well as different classes of diabetes drugs like Ozempic or Mounjaro.

They are identical in active ingredient, dosage form, and effectiveness. The primary difference is the labeling and, most significantly, the price. Authorized generics are sold by the brand-name manufacturer under a private label at a much lower cost.

Yes, Zydus Pharmaceuticals offers patient assistance programs for eligible patients who are uninsured or underinsured and meet specific financial criteria. Enrollment details can be found through healthcare providers or program websites.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.