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Does Adderall Get into Breast Milk? A Guide for Nursing Mothers

4 min read

Between 2003 and 2015, the number of privately insured women aged 15-44 who filled a prescription for an ADHD medication increased by 344%. For these mothers, a critical question arises: does Adderall get into breast milk and is it safe for their baby?

Quick Summary

Yes, Adderall passes into breast milk in small amounts. While studies suggest low risk of adverse effects in infants at therapeutic doses, monitoring for side effects like irritability and poor sleep is crucial. The decision requires a risk-benefit analysis with a healthcare provider.

Key Points

  • Adderall in Milk: Yes, Adderall passes into breast milk, with the infant receiving an estimated 1.8% to 6.9% of the mother's weight-adjusted dose.

  • Infant Effects: At prescribed therapeutic doses, studies have not reported significant adverse effects on infants, but the long-term effects are unknown.

  • Monitoring is Crucial: Mothers should monitor their babies for potential side effects such as irritability, insomnia, poor feeding, and changes in weight gain.

  • Risk-Benefit Analysis: The decision to use Adderall while nursing requires a careful discussion with a healthcare provider, balancing maternal mental health with potential infant risks.

  • Minimizing Exposure: Exposure can be reduced by taking the medication immediately after breastfeeding and using the lowest effective dose.

  • Alternative Medications: Methylphenidate (Ritalin) is often considered a preferred alternative due to more extensive research and very low levels found in breast milk.

  • Maternal Health Matters: Untreated maternal ADHD can have negative impacts, making effective management crucial during the postpartum period.

In This Article

Understanding Adderall and its Role

Adderall is a combination of amphetamine and dextroamphetamine, a central nervous system (CNS) stimulant primarily prescribed to manage symptoms of Attention Deficit Hyperactivity Disorder (ADHD). For many women, continuing this medication postpartum is essential for managing daily life and mental health. However, the decision becomes complex when breastfeeding, as the well-being of the infant is a primary concern. The use of ADHD medication among women of childbearing age has seen a significant increase, making this a pertinent issue for many new mothers. A CDC report noted a 344% increase in ADHD medication prescriptions among privately insured women aged 15-44 from 2003 to 2015.

Does Adderall Get into Breast Milk?

Yes, Adderall is excreted into breast milk. Research indicates that a small percentage of the maternal dose, estimated to be between 1.8% and 6.9%, reaches the infant through breast milk. This is known as the relative infant dose (RID). One study found the RID of dextroamphetamine to be around 5.7%. While these levels are generally considered low, the fact that the drug is transferred to the infant necessitates careful consideration and monitoring. The concentration of the medication in breast milk is directly related to the level in the mother's bloodstream.

Potential Effects on a Breastfed Infant

Although available data is limited, existing studies on mothers taking prescribed therapeutic doses of amphetamines have not reported significant adverse effects in their infants. However, because Adderall is a powerful stimulant, healthcare providers recommend monitoring the baby closely.

Potential signs to watch for in the infant include:

  • Irritability or agitation
  • Insomnia or poor sleep patterns
  • Decreased appetite or poor feeding
  • Poor weight gain
  • Tremors

It's important to distinguish these potential side effects from normal infant behavior. If any of these symptoms are observed, consulting with a pediatrician is essential. The long-term effects of this exposure on infant development are not yet well understood.

Medical Recommendations and a Risk-Benefit Analysis

The decision to use Adderall while breastfeeding involves a careful risk-benefit analysis conducted with a healthcare provider. Untreated maternal ADHD can also pose risks to both mother and child, highlighting the importance of managing the mother's mental health postpartum.

Most medical bodies advise caution. The FDA advises against breastfeeding for mothers who take amphetamines due to the unknown long-term effects. However, many providers will support continued use if the benefits for the mother's health are significant and the dose is kept low. Generally, amphetamine doses up to 35 mg per day are considered compatible with breastfeeding, with close infant monitoring.

Approach Pros Cons Considerations
Continue Adderall Mother's ADHD symptoms are managed, improving her ability to care for the infant and her overall well-being. Potential risk of side effects in the infant (e.g., irritability, poor sleep). Unknown long-term effects. Potential for decreased milk supply at high doses. Use the lowest effective dose. Monitor the infant closely for any changes. Time doses around feedings.
Switch Medication Methylphenidate (Ritalin) is often considered a preferred alternative as it has been studied more extensively and shows very low levels in breast milk. Non-stimulant options may also be considered. New medication may be less effective for the mother or have different side effects. Discuss with a provider to see if an alternative is a suitable and effective option for managing ADHD symptoms.
Discontinue Medication Eliminates any risk of infant exposure to the medication through breast milk. Return of mother's ADHD symptoms, which can impact mental health and daily functioning. This may be an option for those with mild symptoms, often combined with non-pharmacological treatments like therapy or coaching.

Strategies to Minimize Infant Exposure

If a mother and her doctor decide to continue with Adderall, there are strategies to minimize the baby's exposure:

  • Time Your Dose: Take the medication immediately after a breastfeeding session. This allows for the maximum amount of time to pass before the next feeding, as drug concentrations in milk will be lowest right before the next dose.
  • Choose Formulations Wisely: Immediate-release (IR) formulations peak in the bloodstream (and thus, milk) about 1-2 hours after being taken. Extended-release (XR) versions have more sustained levels for 6-8 hours. Using an IR formulation may offer more flexibility in timing feedings to avoid peak concentrations.
  • Use the Lowest Effective Dose: Work with your doctor to find the minimum dose that effectively manages your symptoms.
  • Monitor Your Baby: Keep in close contact with your pediatrician to monitor your infant's growth, sleep, and temperament.

Conclusion

Adderall does pass into breast milk, but in low amounts that have not been shown to cause harm in the few infants studied when the mother is taking a prescribed, therapeutic dose. The decision is a personal one that requires a thorough discussion between the mother, her partner, and her healthcare team, weighing the crucial need for maternal mental health against the potential, though seemingly low, risks to the infant. Close monitoring and strategic dosing can help mitigate risks. For more detailed, individualized advice, consulting resources like the InfantRisk Center is recommended.


Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before making any decisions about your health or treatment.

InfantRisk Center

Frequently Asked Questions

Studies estimate that the relative infant dose is between 1.8% and 6.9% of the mother's dose, which is generally considered a low level of exposure.

Potential side effects for a nursing infant include irritability, poor sleep patterns, decreased appetite, and poor weight gain. It is important to monitor your baby closely and consult a pediatrician if you have concerns.

While data is limited, existing studies on therapeutic doses have not found significant short-term adverse effects in infants. However, the decision requires a thorough risk-benefit analysis with your doctor, as the long-term effects are unknown.

To minimize exposure, you can take your medication right after a feeding session, use the lowest effective dose, and consider using an immediate-release formula to better time feedings around peak medication levels in your milk.

Yes, methylphenidate (Ritalin) is often suggested as a preferred alternative because more safety data is available and it passes into breast milk at very low levels. Non-stimulant options like bupropion might also be considered.

High doses of amphetamines might interfere with the hormone prolactin, which could potentially reduce milk supply, especially when lactation is first being established. This is less of a concern at typical therapeutic doses.

This may not be necessary if you are on a stable, therapeutic dose. It's more effective to time your dose right after a feeding to minimize the amount of medication in your milk during the next feed. For occasional high doses or non-clinical use, withholding breastfeeding for 24 hours is advised.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.