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Expert Guide: What medication is injected in a stellate ganglion block?

4 min read

The stellate ganglion block procedure can take as little as 15 minutes to perform. A key component of this minimally invasive treatment is understanding what medication is injected in a stellate ganglion block to temporarily interrupt nerve signals and provide relief for a variety of conditions.

Quick Summary

A stellate ganglion block uses local anesthetics, such as bupivacaine, ropivacaine, or lidocaine, injected near a neck nerve cluster to interrupt sympathetic nerve signals for diagnostic or therapeutic purposes. Corticosteroids are sometimes added to reduce inflammation.

Key Points

  • Local Anesthetics Are the Core: The primary medications injected in a stellate ganglion block are local anesthetics, such as bupivacaine, ropivacaine, and lidocaine, which temporarily numb the nerves.

  • Steroids Can Be Added: For therapeutic purposes, an anti-inflammatory corticosteroid like dexamethasone or triamcinolone may be combined with the anesthetic to provide more prolonged relief by reducing nerve inflammation.

  • Diagnostic vs. Therapeutic Use: Local anesthetics are used for diagnostic blocks to confirm sympathetically maintained pain, while a steroid is often added for therapeutic blocks to extend the anti-inflammatory effect.

  • Duration Varies: The choice of anesthetic influences the duration of the effect; faster-acting lidocaine offers shorter relief, while longer-acting bupivacaine and ropivacaine provide more sustained results.

  • Imaging Guidance Is Crucial: The injection is performed using image guidance, such as ultrasound or fluoroscopy, to ensure accurate and safe placement of the needle and medication near the stellate ganglion.

  • Mechanism of Action: The medication blocks or resets sympathetic nerve signals, which can reduce chronic pain, swelling, and other symptoms associated with conditions like CRPS and PTSD.

In This Article

What Is a Stellate Ganglion Block?

A stellate ganglion block (SGB) is an injection procedure targeting the stellate ganglion, a cluster of nerves in the neck that is part of the sympathetic nervous system. This nerve cluster is responsible for transmitting certain types of nerve signals from the head, neck, chest, and upper extremities. When these nerves become overactive due to trauma, injury, or other causes, they can contribute to chronic pain conditions. By temporarily blocking the nerve signals, an SGB aims to diagnose the source of pain and provide relief by essentially resetting the nerves. The success of this procedure hinges on the precise injection of specific medications, typically guided by imaging techniques like ultrasound or fluoroscopy.

The Primary Medications: Local Anesthetics

The cornerstone of any stellate ganglion block is a local anesthetic. These are numbing agents that temporarily stop nerve signals, thereby interrupting the pain or anxiety-related signals from the sympathetic nervous system. The choice of anesthetic often depends on whether the block is for diagnostic or therapeutic purposes, and the desired duration of effect. For diagnostic blocks, which aim to confirm if the sympathetic nervous system is the source of the patient's symptoms, a faster-acting anesthetic might be preferred. For therapeutic blocks, a longer-lasting effect is often sought.

Common local anesthetics used include:

  • Bupivacaine: A long-acting local anesthetic commonly used for therapeutic blocks to provide extended relief.
  • Ropivacaine: Another long-acting anesthetic, chemically similar to bupivacaine, also used for prolonged relief. It's often used in advanced protocols for treating conditions like PTSD.
  • Lidocaine: A faster-acting anesthetic that provides rapid, but shorter-term, numbing. It may be used for initial numbing or for diagnostic blocks.
  • Mepivacaine: An intermediate-acting anesthetic that can also be used in SGB procedures.

Combining with Anti-inflammatory Steroids

In many cases, especially for therapeutic purposes, the local anesthetic is combined with a corticosteroid, an anti-inflammatory medication. While the anesthetic provides immediate but temporary nerve signal interruption, the steroid's role is to reduce the inflammation around the nerve cluster, which can lead to longer-lasting symptom relief.

Common corticosteroids include:

  • Dexamethasone: A potent anti-inflammatory agent that can be added to the anesthetic mixture.
  • Triamcinolone: Another steroid used to help manage inflammation and prolong the block's therapeutic effect.

It is important to note that the decision to include a steroid is made by the physician based on the patient's condition and the block's purpose. For purely diagnostic blocks, only the local anesthetic may be used to isolate the sympathetic nerve's role without the confounding effect of inflammation reduction.

Comparison of Medications Used in Stellate Ganglion Blocks

To better understand the different medications, here is a comparison based on their typical use in a stellate ganglion block procedure:

Medication Type Primary Function Typical Use Case Duration of Effect
Bupivacaine/Ropivacaine Local Anesthetic Numbing/Blocking Nerve Signals Therapeutic blocks for prolonged relief Long-acting (several hours)
Lidocaine Local Anesthetic Numbing/Blocking Nerve Signals Diagnostic blocks, initial numbing Short-acting (1-2 hours)
Corticosteroids Anti-inflammatory Reducing Inflammation Therapeutic blocks for extended effect Long-term (days to weeks)

How a Stellate Ganglion Block is Performed

The procedure is a precise outpatient treatment, often performed by an anesthesiologist or a pain management specialist. The patient typically lies on their back while vital signs are monitored. The injection site in the neck is cleaned with an antiseptic solution. Imaging guidance, either fluoroscopy (X-ray) or ultrasound, is used to ensure the needle is accurately placed near the stellate ganglion, avoiding nearby structures like blood vessels and nerves. A contrast dye might be injected to confirm correct needle placement. Once the needle is in the right position, the medication—typically a mix of local anesthetic and sometimes a steroid—is slowly injected. The entire process is relatively quick, taking only a few minutes for the injection itself.

After the injection, the patient is monitored for a short period. As the medication takes effect, temporary side effects are common and expected. These include Horner's syndrome (a constellation of symptoms including a drooping eyelid and constricted pupil), redness of the eye, hoarseness, and a stuffy nose on the injected side. These symptoms are temporary and are considered a sign of a successful block, confirming that the sympathetic nerves were affected.

Conclusion

In summary, the medication injected in a stellate ganglion block is most commonly a local anesthetic, such as bupivacaine, ropivacaine, or lidocaine, which temporarily interrupts sympathetic nerve signals. For blocks aimed at long-term therapeutic relief, these anesthetics are frequently combined with an anti-inflammatory corticosteroid to reduce inflammation and enhance the lasting effects. This targeted pharmacological approach, guided by imaging, allows for a precise diagnostic and therapeutic intervention for a range of conditions, from chronic pain syndromes to certain anxiety disorders. The selection and combination of these medications are tailored by the physician to suit the specific needs of the patient and the goals of the block. For more information, consult authoritative medical resources like those available through the National Institutes of Health.(https://www.ncbi.nlm.nih.gov/books/NBK507798/)

Frequently Asked Questions

The primary medication used is a local anesthetic, most commonly bupivacaine, ropivacaine, or lidocaine.

No, steroids are not always included. They are often added for therapeutic purposes to reduce inflammation for longer-lasting relief, but for diagnostic blocks, only a local anesthetic is typically used.

The main difference is the duration of their effect. Lidocaine is faster-acting but provides shorter relief, while bupivacaine and ropivacaine are longer-acting, offering more sustained numbing of the nerves.

The local anesthetic blocks the nerve signals of the stellate ganglion, which is part of the sympathetic nervous system. In CRPS, this system can be overactive, so blocking the signals helps to reset the nerve activity and relieve associated pain, swelling, and circulation issues.

No, the medication is injected into the fascial plane around the stellate ganglion. Image guidance (fluoroscopy or ultrasound) is used to ensure precise placement near the nerve cluster, not directly into it.

Pain may return as the local anesthetic wears off after several hours. However, the therapeutic effect of the block, especially when a steroid is included, can last much longer, potentially weeks or months.

Knowing the medications helps you understand the procedure's purpose and expected effects. It also informs your doctor of any allergies you may have to the specific agents used, ensuring your safety during the procedure.

While some patients experience long-term or permanent relief, most find that the effect is temporary. A series of blocks may be necessary to achieve sustained improvement.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.