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How do you mix Maalox and Benadryl for canker sores? A guide to the DIY 'Magic Mouthwash'

4 min read

While canker sores often heal on their own within 7 to 14 days, the pain and discomfort can be significant. For temporary relief, many turn to a popular over-the-counter mixture, and here is how you mix Maalox and Benadryl for canker sores. This combination can help soothe irritation and provide a protective coating over the sores.

Quick Summary

This guide provides instructions for creating an over-the-counter rinse by mixing Maalox and Benadryl for temporary relief of canker sore pain. It explains the purpose of each ingredient, details the mixing process, outlines safety precautions, and compares this DIY solution with other common treatments.

Key Points

  • Mix Equal Parts: Combine liquid Maalox (aluminum hydroxide/magnesium hydroxide) and liquid Benadryl (diphenhydramine) in a 1:1 ratio.

  • Coat and Numb: Maalox provides a protective coating for the sore, while Benadryl offers a temporary numbing effect to relieve pain.

  • Swish and Spit: Use a small amount of the mixture, swish for one minute, and then spit it out completely to avoid drowsiness from swallowing the Benadryl.

  • Wait Before Eating: To allow the coating to take effect, avoid eating or drinking for at least 30 minutes after using the rinse.

  • Consult a Professional: If canker sores are severe, persistent, or accompanied by other symptoms, seek medical advice.

  • Avoid Aspirin-Containing Antacids: Never substitute Maalox with products like Kaopectate or Pepto-Bismol, as they can worsen irritation.

In This Article

Canker sores, also known as aphthous ulcers, are small lesions that form on the soft tissues inside the mouth and can cause significant pain, especially when eating or speaking. A popular at-home remedy, often referred to as a "lite" version of prescription "Magic Mouthwash," involves combining over-the-counter liquid Benadryl and Maalox. This mixture is designed to provide temporary relief by coating and protecting the irritated tissue and helping to reduce the sensation of pain.

The Role of Each Ingredient

To understand why this mixture works, it's helpful to know the function of each component:

  • Maalox (or a generic equivalent of aluminum hydroxide/magnesium hydroxide): This antacid serves as the coating agent in the mixture. It adheres to the sore, creating a physical barrier that protects the ulcer from irritants like acidic foods, beverages, or spicy foods. This protective layer allows the sore to heal without constant irritation, providing relief from discomfort. The coating also helps the antihistamine stay in contact with the sore.
  • Liquid Benadryl (diphenhydramine hydrochloride): The antihistamine in Benadryl helps reduce pain and inflammation. When used as a rinse and spit, the diphenhydramine can act as a local anesthetic, providing a numbing effect that helps manage the pain associated with the canker sore.

Step-by-Step Mixing Instructions

Creating this over-the-counter mouth rinse is a straightforward process. It is important to only use liquid diphenhydramine (Benadryl) and a liquid antacid containing aluminum hydroxide and magnesium hydroxide (Maalox or Mylanta). Do not use antacids containing aspirin or bismuth subsalicylate, such as Kaopectate or Pepto-Bismol, as they can cause further irritation.

  1. Gather your ingredients: You will need liquid Maalox (or a suitable generic equivalent) and liquid Benadryl (diphenhydramine).
  2. Combine ingredients: Mix equal amounts of both liquids. The exact quantity can be adjusted based on the area of the mouth being treated.
  3. Shake well: Stir or shake the mixture thoroughly until it is well combined.
  4. Swish and spit: Use a small amount of the mixture, swish it around in your mouth for about one minute, and then spit it out completely. The liquid is for topical use in the mouth and should not be swallowed.
  5. Refrigerate: Storing the mixture in the refrigerator can provide a cooling, soothing sensation upon application.

Safety Precautions and Best Practices

While this remedy is widely used, it is important to take certain safety precautions:

  • Do not swallow the rinse: The primary risk is swallowing the diphenhydramine, which can cause drowsiness. The Maalox is generally safe if swallowed, but the Benadryl component means the mixture should be spit out.
  • Use as needed: The rinse is intended for temporary relief and should be used according to package directions or as advised by a healthcare professional.
  • Avoid eating or drinking immediately after: For the coating to be effective, avoid consuming food or liquids for at least 30 minutes after using the rinse.
  • Consult a professional: If canker sores are large, persistent for more than two weeks, or if you experience a fever or illness alongside them, you should consult a healthcare specialist. This is especially important for children, who should only use this under a doctor's guidance.

Comparison of Canker Sore Remedies

Remedy Pros Cons Best For
Maalox/Benadryl Rinse Easy to make with OTC ingredients. Provides both coating and anesthetic effect. Can cause drowsiness if swallowed. Not a cure, only symptomatic relief. Temporary relief for moderate to severe pain, especially before meals or bedtime.
Saltwater Rinse Simple, cheap, and effective for cleansing and reducing inflammation. Can be painful if salt gets directly on the sore. Offers no coating or numbing effect. Mild pain, general mouth cleansing, and flushing out debris.
OTC Numbing Gels Applied directly to the sore for targeted numbing (e.g., Orajel, Anbesol). Numbing effect is often short-lived. Can be messy to apply to hard-to-reach areas. Quick, localized pain relief for small, easily accessible canker sores.
Prescription 'Magic Mouthwash' Often includes stronger numbing agents (viscous lidocaine), steroids, or antifungals for more potent relief. Requires a doctor's prescription. May have more side effects. Severe, persistent canker sores or those associated with other systemic issues.

Conclusion: Responsible Use of Canker Sore Remedies

The DIY mixture of Maalox and Benadryl is a widely known remedy for the pain of canker sores, offering temporary relief by coating the area and providing a localized numbing effect. However, it is not a cure and should be used with caution, particularly by ensuring the mixture is spit out completely. While effective for temporary management of discomfort, it is crucial to consult a doctor if canker sores are severe, unusually large, or do not show signs of healing within two weeks. For many, simple home remedies like saltwater rinses or over-the-counter gels may also provide sufficient relief. Always prioritize safety and professional medical advice when dealing with persistent or severe health issues like recurring mouth sores. For more information on general canker sore management, see the Cleveland Clinic's guidance.

Frequently Asked Questions

The Maalox coats the canker sore, providing a protective barrier against irritation, while the liquid Benadryl acts as a local anesthetic, offering a temporary numbing effect to reduce pain.

No, you should only use liquid antacids containing aluminum hydroxide/magnesium hydroxide, like Maalox or Mylanta. Avoid antacids with bismuth subsalicylate (e.g., Kaopectate, Pepto-Bismol) as they can cause further irritation.

No, you should always spit out the mixture after swishing. Swallowing the liquid Benadryl can cause unwanted side effects, most notably drowsiness.

The rinse is typically used as needed for temporary relief. The best times are often before meals or bedtime to help manage discomfort. Consult packaging for specific usage instructions.

Prescription 'Magic Mouthwash' often contains additional, more potent ingredients like viscous lidocaine for stronger numbing, or even steroids or antifungals. The OTC Maalox and Benadryl mix is a simpler, less powerful version.

Yes, alternatives include saltwater rinses, baking soda rinses, or applying over-the-counter numbing gels like Orajel or Anbesol. For persistent issues, a healthcare professional can offer more advanced treatments.

You should consult a doctor before using any medication-based remedy for a child, even over-the-counter ones. A doctor or dentist can provide guidance on appropriate treatments and dosages for children.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.