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How do you use Oraltek? A Patient's Guide to Sublingual Immunotherapy

4 min read

More than 50% of patients with asthma may have started with allergic rhinitis. Sublingual immunotherapy (SLIT) like Oraltek treats the root cause, not just symptoms. So, how do you use Oraltek effectively and safely at home?

Quick Summary

A detailed explanation of the proper administration for Oraltek, a sublingual immunotherapy spray for allergies. It covers the daily procedure, general administration principles, managing side effects, and key patient tips for successful treatment.

Key Points

  • What it is: Oraltek is a sublingual immunotherapy (SLIT) spray used to treat the root cause of allergies like allergic rhinitis and asthma.

  • Administration: The medication is sprayed under the tongue, held for 1-2 minutes, and then swallowed daily.

  • Administration Phases: Treatment involves an initial potential build-up phase followed by a long-term maintenance phase lasting 3-5 years.

  • Consistency is Crucial: Oraltek must be taken daily as prescribed to be effective in building immune tolerance.

  • Safety Profile: The risk of severe allergic reactions is very low; common side effects are mild and transient, such as oral itching.

  • At-Home Convenience: Unlike allergy shots, Oraltek is administered at home, eliminating the need for frequent clinic visits.

  • Professional Guidance: Oraltek is a prescription treatment that requires diagnosis and monitoring by an allergist or physician.

In This Article

What is Oraltek? An Overview of Sublingual Immunotherapy (SLIT)

Oraltek is a specific brand of sublingual immunotherapy (SLIT), a medical treatment for allergic diseases such as allergic rhinitis and asthma. Unlike medications that only manage symptoms, SLIT aims to treat the root cause of the allergy. The therapy works by administering small, controlled doses of a specific allergen (like pollen, dust mites, or pet dander) under the tongue. This process helps your immune system gradually build tolerance, desensitizing it to the allergen over time and reducing the severity of allergic reactions. Oraltek is typically delivered as a sublingual spray, which provides wide coverage of the oral mucosa. This method is considered a viable and safe alternative to traditional allergy shots (subcutaneous immunotherapy) and can be administered at home.

Who is a Candidate for Oraltek Treatment?

Oraltek is prescribed by a doctor after allergy testing confirms sensitivity to specific airborne allergens. It is indicated for both adults and children (often over the age of two) suffering from conditions like allergic rhinitis (hay fever), conjunctivitis, and allergic asthma. Patients who are good candidates are typically those with allergies to common inhaled allergens such as:

  • House dust mites
  • Grass and tree pollens
  • Animal dander
  • Mold

This treatment requires consistent, long-term commitment, as the standard duration is three to five years to achieve lasting immunity. Therefore, candidates must be able to adhere to a daily administration schedule.

The Core Question: How do you use Oraltek? A Step-by-Step Guide

Proper administration is crucial for the effectiveness and safety of Oraltek. While your doctor will provide specific instructions, the general process for using the sublingual spray is as follows:

  1. Preparation: Before the first use of a new vial, you may need to prime the pump by spraying it 3 or 4 times away from your face until a fine mist is produced. Shake the bottle gently before each use.
  2. Position the Nozzle: Lift your tongue towards the roof of your mouth. Aim the nozzle of the Oraltek spray directly into the space underneath your tongue (the sublingual area).
  3. Administer the Medication: Press down firmly on the pump to deliver the prescribed amount of medication. The specific number of sprays will be determined by your healthcare provider.
  4. Hold the Solution: Keep the liquid under your tongue for one to two minutes without swallowing. This allows the allergen extract to be absorbed by the specialized immune cells in the oral mucosa.
  5. Swallow: After the holding period, swallow the remaining solution.
  6. Post-Administration Care: To ensure maximum absorption, you should not eat, drink, or brush your teeth for a specified period after taking your dose, typically at least 15 to 30 minutes.

It is recommended to take Oraltek at the same time each day, preferably on an empty stomach.

Understanding Your Oraltek Administration and Schedule

Sublingual immunotherapy often involves different phases of administration as determined by a healthcare professional:

  • Build-Up (Escalation) Phase: Some SLIT treatments begin with a build-up phase, where the amount or concentration is gradually increased over a period of days or weeks. This helps your body get accustomed to the allergen.
  • Maintenance Phase: Once the target amount is reached, you enter the maintenance phase. During this time, you take a consistent, daily amount of the allergen extract. This phase typically lasts for three to five years to achieve a long-term therapeutic effect.

Your allergist will design a personalized treatment plan and schedule for you. Regular follow-up appointments are necessary to monitor your progress and make any adjustments.

Potential Side Effects and Management

Oraltek is generally considered safe, with a very low risk of severe reactions. However, some mild to moderate side effects can occur, especially at the beginning of treatment. The most common is oral itching (oral pruritus) or mild swelling of the lips, mouth, or tongue. These reactions are usually temporary and resolve as your body adapts.

Other less common side effects may include:

  • Nausea, vomiting, or abdominal pain
  • Eye itching or redness
  • Sneezing or nasal congestion
  • Skin reactions like hives

A rare but more serious side effect is eosinophilic esophagitis, an inflammation of the esophagus that can cause difficulty swallowing. If you have any open sores or wounds in your mouth, you should temporarily stop treatment until they have healed to prevent the allergen from entering the bloodstream too quickly.

Oraltek (SLIT) vs. Other Allergy Treatments: A Comparison

Feature Oraltek (SLIT Drops/Spray) Allergy Shots (SCIT) Antihistamines
Administration At home, daily drops/sprays under the tongue. In-office weekly or monthly injections. As-needed oral pills or nasal sprays.
Goal Builds long-term tolerance to allergens. Builds long-term tolerance to allergens. Provides temporary relief from symptoms.
Convenience High; no frequent clinic visits required. Low; requires regular trips to the doctor's office and a waiting period after each shot. High; readily available over-the-counter or by prescription.
Onset of Relief Symptom improvement can be seen in 3-4 months. Symptom improvement can be seen in 6-8 months. Fast-acting for immediate symptom relief.
Safety Profile Very low risk of severe systemic reactions (anaphylaxis). Higher risk of systemic reactions; requires medical supervision. Generally safe, with potential side effects like drowsiness.
Insurance Coverage Varies; SLIT drops are often not covered by insurance, though FDA-approved tablets may be. Generally covered by most insurance plans. Generally covered or inexpensive.

Conclusion: A Modern Approach to Allergy Management

Oraltek and other forms of sublingual immunotherapy represent a significant advancement in allergy treatment, offering a safe and convenient way to address the underlying cause of allergies rather than just masking the symptoms. By following the prescribed step-by-step administration process and adhering to the daily schedule, patients can gradually build tolerance to allergens, leading to a long-term reduction in symptoms and an improved quality of life. Consistent communication with your allergist is essential to monitor progress, manage any side effects, and ensure the best possible outcome from your treatment.

For more detailed information from a manufacturer, you can review patient materials, such as this one from Inmunotek.

Frequently Asked Questions

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one. Do not take a double dose. If you miss treatment for more than one week, you should contact your clinic for advice before restarting.

No. You should avoid eating, drinking, or brushing your teeth for at least 15 to 30 minutes after taking Oraltek to allow for maximum absorption of the medication under your tongue.

The most common side effect is mild, temporary itching or swelling in the mouth, on the lips, or under the tongue. These symptoms typically decrease over time as treatment continues.

Many patients begin to notice an improvement in their allergy symptoms within three to four months of starting daily treatment. However, the full therapeutic effect requires completing the entire 3 to 5-year course.

Yes, Oraltek is considered safe and is indicated for use in children, often for those over the age of two, for treating allergic respiratory diseases. A doctor must prescribe and oversee the treatment.

It is typically recommended to store Oraltek vials in the refrigerator at a temperature of 2-8°C (36-46°F). Do not freeze the product.

No, you should generally continue your standard allergy medications when you begin Oraltek. Over time, as the immunotherapy takes effect, you may find that your need for these other medications is reduced.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.