Understanding Finasteride and Male Pattern Baldness
Male pattern baldness, or androgenetic alopecia (AGA), is responsible for over 95% of hair loss in men [1.8.2]. The condition is linked to genetics and the hormone dihydrotestosterone (DHT) [1.2.4]. Testosterone is converted into DHT by an enzyme called 5-alpha-reductase [1.9.2]. In genetically predisposed individuals, DHT binds to receptors in the scalp and causes hair follicles to shrink, a process known as miniaturization. This shortens the hair's growth phase (anagen phase), leading to thinner, shorter hairs and eventual hair loss [1.4.1, 1.2.4].
Finasteride is a 5-alpha-reductase inhibitor. It works by blocking this enzyme, specifically the Type II isoenzyme, which prevents testosterone from converting into DHT [1.9.1, 1.9.3]. A daily 1 mg dose of finasteride can lower DHT levels in the scalp and serum by about 70%, which is enough to significantly slow, stop, and in some cases, reverse the miniaturization process [1.2.1, 1.2.4].
The Finasteride Results Timeline
Finasteride's effects aren't immediate and require patience and consistency. While the medication starts reducing DHT levels within 24 hours of the first dose, visible changes to your hair take several months due to the natural hair growth cycle [1.4.1].
Months 1-3: The Foundation Phase
During the first few months, you are unlikely to see noticeable improvements. The medication is working internally to lower DHT and protect your follicles, but it's too early for new, healthier hairs to have grown to a visible length. Some users may even experience a temporary shedding phase as thinner hairs are pushed out to make way for new growth [1.4.4, 1.4.5]. It is crucial to continue taking the medication daily during this period [1.4.1].
Months 3-6: Initial Improvements
Between three and six months, initial results often become apparent. You may notice that your hair loss has slowed down or stopped completely. Some regrowth, particularly at the crown (vertex) and mid-scalp, might become visible [1.4.1, 1.4.4]. One study noted significant improvement in men after just 12 weeks of use [1.4.1].
Month 12 and Beyond: Noticeable and Sustained Results
After one year of consistent daily use, the results of finasteride should be much more noticeable. Studies show significant increases in hair count and thickness [1.4.1]. About 83% of men with vertex hair loss using finasteride showed no further hair loss after two years [1.2.3].
Long-term studies confirm its sustained effectiveness. A 5-year study found that 90% of men taking finasteride experienced either improvement (48%) or no further hair loss (42%) [1.2.4]. A 10-year study in Japan involving over 500 men found that 91.5% showed improvement, with effectiveness being higher in men younger than 40 and those in earlier stages of hair loss [1.3.3, 1.3.5]. The key takeaway is that finasteride is a long-term treatment. It works as long as you take it [1.4.2].
Comparison Table: Finasteride vs. Other Hair Loss Treatments
Feature | Finasteride (Propecia) | Minoxidil (Rogaine) | Dutasteride (Avodart) |
---|---|---|---|
Mechanism | Oral 5-alpha reductase (Type II) inhibitor, reduces scalp DHT [1.9.1, 1.9.3]. | Topical vasodilator, increases blood flow to follicles and widens them [1.7.2, 1.4.1]. | Oral 5-alpha reductase (Type I & II) inhibitor, more potent DHT suppression [1.6.3, 1.6.5]. |
Application | Once-daily oral pill (1 mg for hair loss) [1.10.1, 1.10.2]. | Topical solution or foam applied to the scalp, typically twice daily [1.4.5]. | Once-daily oral pill (0.5 mg), off-label for hair loss in many regions [1.6.1, 1.6.3]. |
Efficacy | Highly effective; halts progression in ~90% of men over 5 years [1.2.4]. | Less effective than finasteride for halting progression, but effective for regrowth [1.6.4]. Combination therapy is synergistic [1.4.1]. | Considered the most effective of the three, with greater DHT suppression (~98%) and hair count increase [1.6.3, 1.6.5]. |
Side Effects | Rare but include sexual side effects (decreased libido, erectile dysfunction) in a small percentage of users [1.7.1, 1.7.2]. | Scalp irritation, unwanted facial hair growth (hypertrichosis) [1.6.4]. | Similar side effect profile to finasteride but may be more frequent due to higher potency [1.6.4, 1.6.5]. |
What Happens if You Stop Taking Finasteride?
The benefits of finasteride are not permanent and depend on continuous use [1.2.1]. If you stop taking the medication, your body's DHT levels will return to their previous baseline within about two weeks [1.5.4]. Consequently, the hair loss process will resume. Most men find that any hair they maintained or regrew due to the treatment will be lost within 9 to 12 months of stopping [1.5.1, 1.5.2]. Starting and stopping the medication is not recommended, as you will likely lose ground compared to continuous use [1.2.4].
Potential Side Effects and Considerations
While generally well-tolerated, finasteride can cause side effects. The most discussed are sexual in nature, including decreased libido, erectile dysfunction (ED), and issues with ejaculation [1.7.1]. Clinical trials show these affect a small percentage of users (e.g., 1.4% to 1.9%) [1.2.4, 1.7.4]. For many, these side effects decrease with continued use or resolve after stopping the drug [1.2.4]. However, there are reports of persistent side effects after discontinuation, a condition sometimes referred to as Post-Finasteride Syndrome (PFS), though its true incidence is unknown [1.5.3, 1.5.5].
Other potential side effects include breast tenderness or enlargement (gynecomastia), testicular pain, and mood changes like depression [1.7.1, 1.7.3]. It's crucial to discuss your medical history and any concerns with a healthcare provider before starting treatment.
An Important Note for Women
Finasteride is not FDA-approved for hair loss in women and is contraindicated for those who are or may become pregnant [1.11.1, 1.11.2]. It can cause severe birth defects in a male fetus. Women should not handle broken or crushed finasteride tablets [1.7.3].
Conclusion
Finasteride is a clinically proven, effective long-term treatment for male pattern baldness that can preserve hair for many years—as long as it is taken consistently. Studies demonstrate its ability to halt hair loss progression and promote regrowth in a vast majority of men, with some studies showing high efficacy even after a decade of use [1.3.3]. The decision to take finasteride should be made in consultation with a doctor, after weighing the significant, sustained benefits against the potential for side effects. For those who commit to the treatment, it remains one of the most powerful tools available in the fight against hair loss.
For further reading on the efficacy and safety of topical finasteride solutions, one alternative to the oral pill, you can review this study published by the National Institutes of Health: Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia [1.2.5].