The Cost of Vabysmo: Breaking Down the Price
The total cost of Vabysmo (faricimab) in Canada varies based on factors like the patient's condition, injection frequency, and insurance coverage. The manufacturer's submitted price for a single-use vial is $1,350.00 CAD.
Per-Vial and Annual Costs
Annual costs for Vabysmo can differ significantly. For the first year of treatment, which may involve 7 to 10 injections, estimates range from approximately $9,450 to $13,500 CAD. Another reported range for the first year is $8,100 to $18,900 CAD, depending on 6 to 14 injections.
In subsequent years, with potentially fewer injections (4 to 7 per year), the estimated annual cost drops to between $5,400 and $9,450 CAD. Other data suggests subsequent annual costs could range from $4,050 to $17,550 CAD based on 3 to 13 injections.
These costs cover the medication only and exclude additional medical fees from ophthalmologists or facilities.
Insurance and Coverage in Canada
In Canada, drug coverage is primarily managed at the provincial level. While public plans are increasingly covering Vabysmo, eligibility varies by province. For instance, Vabysmo is publicly funded in Ontario and Quebec for conditions including wet AMD, DME, and RVO. Alberta also lists Vabysmo on its drug benefit list for DME and AMD. Public coverage typically requires an ophthalmologist's diagnosis and meeting clinical criteria. Most Canadians with private insurance also have Vabysmo coverage, though out-of-pocket costs depend on the specific plan.
Comparison of Vabysmo to Other Anti-VEGF Treatments
Vabysmo is often compared to other anti-VEGF treatments for retinal conditions. The annual costs below are based on Canadian data, and coverage decisions consider cost-effectiveness and patient outcomes.
Feature | Vabysmo (Faricimab) | Eylea (Aflibercept) | Avastin (Bevacizumab) |
---|---|---|---|
Mechanism | Dual inhibition of Ang-2 and VEGF-A | Inhibition of VEGF-A | Inhibition of VEGF-A (off-label use) |
Year 1 Annual Cost (CAD) | ~$9,450 to $13,500 | ~$9,926 to $14,180 (BC) | ~$138 to $173 (BC) |
Subsequent Years Annual Cost (CAD) | ~$5,400 to $9,450 | ~$5,672 to $9,926 (BC) | ~$121 to $156 (BC) |
Injection Frequency | Less frequent injections possible (up to 16 weeks) | Every 8-16 weeks | Every 6-8 weeks (off-label) |
Public Funding | Expanding across provinces | Widely available | Reimbursement in some jurisdictions |
Note: Avastin is used off-label for these eye conditions, and its cost is significantly lower due to its status as a cancer drug packaged for wider use, with multiple doses often derived from a single vial. Cost ranges depend on the number of injections, which varies by patient.
Financial Assistance Options
Several financial assistance options are available for patients struggling with Vabysmo costs, particularly those without sufficient insurance. Roche Canada, the manufacturer, offers support programs to help patients and healthcare providers navigate reimbursement. Independent charitable organizations in Canada may also provide co-pay assistance for patients with relevant conditions like macular disease. Patients should consult with their ophthalmologist's office or contact Roche Canada directly to explore available options. While based in the US, the Genentech Patient Foundation is part of the broader Roche group and provides an example of the type of manufacturer support that can exist.
Conclusion: Navigating the Costs of Vabysmo
Accessing Vabysmo in Canada requires navigating significant costs, making insurance coverage essential. Public drug plan coverage is expanding across provinces, but eligibility varies. Patients should consult their ophthalmologist and insurer to understand costs and explore financial assistance options.