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How much is the generic version of Restasis?

4 min read

According to pricing data from August 2025, the generic version of Restasis can be purchased for as low as $91 for a one-month supply when using a discount card. However, understanding how much is the generic version of Restasis requires looking beyond the retail price, which can often be significantly higher.

Quick Summary

The generic for Restasis, cyclosporine ophthalmic emulsion, has a high cash price without insurance, but savings are substantial with discount cards or insurance. Factors like pharmacy, location, and dosage impact the final cost.

Key Points

  • Generic Name: The generic version of Restasis is cyclosporine ophthalmic emulsion 0.05% and is considered therapeutically equivalent.

  • Cash Price: Without discounts, the retail price for a 30-day supply of generic cyclosporine can be high, potentially over $700.

  • Discount Card Savings: Using a discount card from services like GoodRx or SingleCare can lower the monthly cost significantly, often to under $100 for 60 vials.

  • Insurance Coverage: Many insurance plans, including Medicare Part D, cover generic cyclosporine, leading to a much lower copayment, sometimes as low as $10.

  • Price Variations: The final cost is influenced by the specific pharmacy, location, insurance plan, and whether discounts are applied.

  • Other Savings Programs: Additional savings can be found through mail-order pharmacies, manufacturer programs, or third-party patient assistance foundations.

In This Article

Understanding the Generic Version of Restasis

Restasis is a brand-name eye drop containing the active ingredient cyclosporine, which is used to treat chronic dry eye disease by increasing the eye's natural ability to produce tears. The FDA approved the first generic version of Restasis in February 2022, making it available as cyclosporine ophthalmic emulsion. This generic version contains the same active ingredient and is considered just as safe and effective as the brand-name product.

The High Price of Generic Cyclosporine Without Discounts

Without insurance or a discount coupon, the cash price for generic cyclosporine ophthalmic emulsion can still be remarkably high. Retail prices for a 30-day supply (60 single-use vials) can range significantly depending on the pharmacy. Some pharmacies might list the average retail price without discounts at over $700, though this is not always the price patients pay. Mark Cuban's Cost Plus Drugs offers a very competitive and much lower price point for a smaller quantity, but for many traditional pharmacies, the initial sticker price can be daunting.

Factors That Determine Your Final Cost

Several variables influence the final price you pay for generic cyclosporine:

  • Insurance Coverage: Many health insurance plans, including Medicare Part D, cover generic cyclosporine. Your copayment will depend on your specific plan's formulary, deductible, and coverage tier.
  • Prescription Discount Cards: Services like GoodRx and SingleCare can dramatically lower the out-of-pocket cost for uninsured or underinsured individuals. These cards can reduce the monthly cost to less than $100.
  • Pharmacy Selection: Prices can vary widely between different pharmacies, even those in the same city. Shopping around or using a prescription comparison tool is essential for finding the lowest price.
  • Dosage Form: Generic cyclosporine is available in single-use vials, while brand-name Restasis is also offered in a MultiDose bottle, for which a generic is not available.
  • Patient Assistance Programs: For those who qualify based on income and insurance status, manufacturer-based or third-party patient assistance programs can offer significant discounts or free medication.

How to Find the Best Price on Generic Cyclosporine

To minimize your out-of-pocket costs for the generic version of Restasis, consider these steps:

  1. Use a prescription savings card: Websites and apps like SingleCare, GoodRx, or SaveHealth offer free coupons that can be used at most major pharmacies.
  2. Compare prices: Before filling your prescription, use online tools to compare pharmacy prices in your area. This simple step can save you a substantial amount of money.
  3. Consider mail-order pharmacies: Some insurance plans offer better prices for a 90-day supply when filled through their mail-order service. Pharmacies like Amazon Pharmacy also offer competitive pricing for members.
  4. Explore patient assistance: For those with low income, various patient assistance programs may offer medication at a very low cost or free of charge. You can investigate programs offered by the manufacturer or through foundations like the Patient Advocate Foundation.

Comparison: Generic vs. Brand-Name Restasis

To illustrate the potential savings, here is a comparison of typical costs for a 30-day supply (60 single-use vials) of generic vs. brand-name Restasis. Keep in mind that prices are estimates and can vary based on location and pharmacy.

Feature Brand-Name Restasis (cyclosporine ophthalmic emulsion) Generic Cyclosporine (cyclosporine ophthalmic emulsion)
Average Retail Price (No Discounts) $689–$822 $629–$791
With Discount Card $135–$411 (varies significantly) As low as $88.66–$135.86
With Standard Insurance Depends on formulary; often requires prior authorization Low copay possible; many plans cover
Patient Assistance Programs AbbVie Patient Assistance available for qualifying patients Third-party foundation programs may be available

Other Dry Eye Treatment Costs

Beyond generic cyclosporine, other prescription options are available, such as Cequa, Vevye, and Xiidra. These medications have different formulations and potentially different mechanisms of action for treating dry eye.

  • Cequa (cyclosporine 0.09% ophthalmic solution): This is a branded cyclosporine product and, like Restasis, can be costly without insurance, although copay cards and patient assistance programs exist.
  • Xiidra (lifitegrast 5% solution): This is another popular treatment with a potentially high cash price, but manufacturer programs and discount cards can help reduce the cost.

Conclusion: Finding Affordable Dry Eye Relief

For individuals with chronic dry eye, finding an affordable treatment can be a challenge, but significant savings are possible, particularly with the generic version of Restasis. While the retail price for generic cyclosporine ophthalmic emulsion can be steep, options like prescription discount cards can bring the monthly cost down significantly. Combining price comparison with the use of insurance or patient assistance programs can help ensure that treatment for this chronic condition is financially manageable. Always consult your healthcare provider to discuss the best treatment option for your specific needs.

For more information on prescription drug pricing and cost-saving tips, you can visit the Healthline website.

Frequently Asked Questions

Yes, a generic version of Restasis is available. The active ingredient is cyclosporine, and the generic is commonly known as cyclosporine ophthalmic emulsion.

With insurance, the cost of generic cyclosporine can vary significantly depending on your plan's formulary, deductible, and copayment structure. Some insurance plans and Medicare Part D often cover the generic, with average copays potentially being low, sometimes around $10.

Without insurance or discounts, the retail price for a 30-day supply (60 single-use vials) can be high, with some estimates exceeding $700. However, prices vary widely by pharmacy.

Yes, prescription discount cards from companies like GoodRx and SingleCare are very effective for lowering the cost of generic cyclosporine. With these coupons, the price can often be brought down to under $100 for a 30-day supply.

The FDA requires generic drugs to be therapeutically equivalent to their brand-name counterparts. This means the generic version of Restasis has the same active ingredient and works in the same way as the brand.

To find the lowest price, it is best to compare prices online using pharmacy comparison tools from sites like GoodRx or SingleCare. Prices vary by pharmacy location and discounts available.

For those who are underinsured or uninsured, patient assistance programs may be available through third-party foundations. While some manufacturer programs specifically cover the brand name, other aid may exist for the generic.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.