Restasis (cyclosporine ophthalmic emulsion) is a prescription medication used to increase tear production in individuals with chronic dry eye disease caused by inflammation. It is not merely an artificial tear but a therapeutic treatment that works over time by targeting the underlying inflammation. To achieve the best results and avoid contamination or injury, it is vital to follow the correct administration procedure. This guide covers how to properly administer Restasis eye drops, including important tips for both single-use vials and the MultiDose bottle.
Preparing to Administer Your Eye Drops
Before applying Restasis, take the following preparatory steps to ensure a clean and effective application:
- Wash your hands: Always wash your hands thoroughly with soap and water before handling the bottle or vial to prevent contamination.
- Check the emulsion: Gently invert the single-use vial or MultiDose bottle a few times. Do not shake it vigorously. The emulsion should appear white and opaque.
- Remove contact lenses: Restasis should not be administered while wearing contact lenses. If you wear contacts, remove them before applying the drops. Wait at least 15 minutes after administering the drops before reinserting your lenses.
- Prime the MultiDose bottle (first use only): If you are using the MultiDose bottle for the first time, prime it by squeezing two drops onto a tissue. This is not necessary for single-use vials.
Step-by-Step Administration Process
Follow these steps for accurate and hygienic administration:
- Tilt your head back and look up toward the ceiling.
- Create a pocket by gently pulling your lower eyelid down with a finger.
- Position the dropper: Hold the inverted vial or bottle with your other hand directly above the pocket you created. Ensure the tip does not touch your eye or any other surface to avoid contamination.
- Instill one drop into the pocket in your lower eyelid.
- Let go of your eyelid and gently close your eye for 1 to 2 minutes. Do not squeeze your eyes shut tightly or blink excessively, as this can cause the medication to drain out.
- Apply gentle pressure to the inner corner of your eye (near your nose) with your finger. This technique, called nasolacrimal occlusion, helps keep the medication in your eye and prevents it from draining into your tear duct.
- Repeat the process for your other eye if instructed by your doctor.
- Wash your hands again to remove any remaining medication.
Single-Use Vials vs. MultiDose Bottle
Restasis is available in two different forms, each with specific handling instructions. The correct method to use depends on which version your doctor has prescribed.
| Feature | Single-Use Vial | MultiDose Bottle |
|---|---|---|
| Preservative | Preservative-free. | Preservative-free, with a special filter to prevent contamination. |
| Usage | Each vial is for a single dose. Use immediately after opening and discard any remaining emulsion. | Each bottle contains multiple doses. Can be used until the expiration date on the bottle. |
| Preparation | Invert gently before each use to mix. | Must be primed before first use (2 drops onto a tissue). Invert gently before each subsequent use. |
| Cost | Can be more expensive, depending on insurance. | Often a more cost-effective option for long-term use. |
| Waste | Designed to be discarded after each use, even if liquid remains. | Less plastic waste per dose due to multiple uses. |
Tips for a Better Administration Experience
- Reduce the sting: A common side effect is a temporary burning or stinging sensation. Refrigerating the drops for a few minutes before use can help alleviate this discomfort. Note: Restasis should not be stored in the refrigerator long-term.
- Consider assistive devices: If you have arthritis, shaky hands, or difficulty with grip, consider using an eye drop guide or a bottle squeezer to improve aim and reduce pressure.
- Time it right: If you need to use artificial tears or other eye drops, always apply Restasis first. Wait at least 15 minutes between different eye drops to ensure each medication has time to absorb fully.
Handling a Missed Dose
Consistency is important for Restasis to be effective. If you miss a dose, here is what you should do:
- Take the missed dose as soon as you remember.
- However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not double up to make up for a missed dose.
Potential Side Effects
While many people tolerate Restasis well, some may experience side effects. The most common adverse reaction is temporary ocular burning or stinging. Other potential side effects include eye redness, itching, discharge, watery eyes, eye pain, and blurred vision. If these side effects are persistent or severe, contact your doctor for advice.
Conclusion
Successfully administering Restasis eye drops requires careful technique and consistency. By following the proper preparation steps and administration technique—including mixing the emulsion, avoiding dropper-tip contamination, and using nasolacrimal occlusion—you can ensure the medication is applied effectively. Understanding the differences between single-use and MultiDose forms is also key to proper use. Consistent, twice-daily use is essential for Restasis to work over time to combat the inflammation that causes chronic dry eye. If you have any difficulties or concerns, your healthcare provider can offer additional guidance or suggest assistive devices.
This is an educational article and not a substitute for professional medical advice. For more detailed prescribing information, consult the official FDA label for Restasis.
