What is Enterosgel?
Enterosgel is a drug-free oral intestinal adsorbent classified as a class IIa medical device. Its active ingredients are 70% polymethylsiloxane polyhydrate and 30% purified water. It is designed to bind to harmful substances in the gut, such as bacterial toxins and allergens, and remove them from the body through stool. It is indicated for the symptomatic treatment of acute diarrhea and Irritable Bowel Syndrome with Diarrhea (IBS-D). Because it is not absorbed into the bloodstream, it is considered to have a favorable safety profile with minimal systemic side effects.
How Does Enterosgel Work?
Enterosgel functions through a process of molecular adsorption. It has a porous, gel-like structure that passes through the digestive system. This structure allows it to selectively bind to medium and large-sized toxic molecules, such as bacterial enterotoxins, endotoxins, and excess bile acids, which are often implicated in gastrointestinal distress. The gel then passes out of the body, taking the bound toxins with it. Studies suggest that its unique adsorption profile is advantageous because it has a lower capacity to bind small molecules, potentially reducing its interaction with essential nutrients and oral medications compared to other adsorbents like activated charcoal. A 2022 double-blind, randomized controlled trial demonstrated its effectiveness in improving stool consistency, abdominal pain, bloating, and urgency in patients with IBS-D.
Step-by-Step Guide: How to Take Enterosgel
Proper administration is crucial for the effectiveness of Enterosgel. It should always be taken relative to meals and other medications to ensure it works correctly without interfering with the absorption of nutrients or drugs.
- Shake the Tube: Before each use, shake the tube well.
- Measure the Dose: Measure the correct dose according to the package instructions or as advised by a healthcare professional. Dosing is typically done three times a day.
- Dilute in Water: Mix the measured dose in a glass of room temperature water. The amount of water for dilution varies by age, so consult the product instructions.
- Consume Immediately: Drink the mixture straight away. If using a sachet, it should be used immediately after opening.
- Timing is Key: Take Enterosgel at least 1–2 hours before or after a meal and at least 2 hours before or after taking any other oral medications. This spacing prevents the gel from binding to the medication and reducing its efficacy.
Duration of Treatment
The recommended duration of use depends on the condition being treated and the advice of a healthcare professional. For acute diarrhea, a shorter course is typical. For chronic conditions like IBS-D, a longer duration may be suggested. Following product instructions and seeking medical advice for specific durations is important.
Enterosgel vs. Activated Charcoal
Enterosgel and activated charcoal are both intestinal adsorbents, but they have different properties and mechanisms of action. A key difference lies in their selective binding capabilities.
| Feature | Enterosgel (Polymethylsiloxane Polyhydrate) | Activated Charcoal |
|---|---|---|
| Mechanism | Adsorbs medium-to-large molecular weight substances like bacterial toxins and bile acids. | Non-selectively adsorbs a wide range of substances, including small molecules. |
| Selectivity | More selective. Has a lower capacity for adsorbing small molecules like vitamins and drugs. | Less selective. Can adsorb medications, vitamins, and nutrients, potentially reducing their effectiveness. |
| Efficacy | Studies show it is effective for acute diarrhea and IBS-D, reducing pain, bloating, and urgency. Has a high capacity for adsorbing bacterial endotoxins. | Effective for acute poisoning and overdose by adsorbing substances in the stomach. Also used for gas and indigestion. |
| Side Effects | Rare, but may include constipation or nausea. It does not damage the intestinal mucosa with long-term use. | Can cause black stools, constipation, and vomiting. Long-term use can lead to depletion of nutrients and vitamins. |
Safety and Precautions
Enterosgel is generally well-tolerated. Side effects are rare but can include constipation and nausea. It is free from sugar, gluten, lactose, preservatives, and common allergens.
Who should avoid Enterosgel?
- Individuals with intestinal atony (severe constipation due to an obstructed bowel) or intestinal blockage.
- Anyone with a known intolerance or allergy to its ingredients.
- Those taking oral modified-release medications, as Enterosgel could interfere with their function.
It can be used during pregnancy and breastfeeding, though consulting a healthcare professional is advisable. Always consult a doctor before giving it to children, particularly those under the age of 3. If symptoms persist for more than a couple of days or are accompanied by fever or blood in the stool, seek medical advice promptly.
Conclusion
Enterosgel offers a targeted approach to managing symptoms of acute diarrhea and IBS-D by physically removing harmful substances from the gut. Its efficacy is supported by clinical research, highlighting its ability to improve stool consistency and reduce abdominal pain, bloating, and urgency. Proper usage, including correct administration according to package instructions or healthcare professional advice, dilution, and timing relative to food and other medications, is essential to maximize its benefits and ensure safety. As with any medical treatment, it is important to follow the package instructions and consult a healthcare professional for diagnosis and guidance, especially for chronic conditions or use in young children.
For more detailed product information, you can visit the manufacturer's website: https://www.enterosgel.eu/en/pribalovy-letak
