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Is Cervidil enough to start labor? Unpacking the induction process

4 min read

Cervidil, containing the hormone-like substance dinoprostone, has been used in over 5 million labor inductions and is the only FDA-approved vaginal insert for this purpose. While highly effective for preparing the cervix, many expectant parents wonder: is Cervidil enough to start labor without further intervention?

Quick Summary

Cervidil is a medication for cervical ripening that may trigger labor, but often requires follow-up treatment like Pitocin to stimulate contractions. Its success depends on several factors, including the state of the cervix.

Key Points

  • Cervidil is primarily for cervical ripening: Its main job is to soften and thin the cervix, a preparatory step for labor, not to forcefully trigger contractions.

  • It may or may not start labor alone: While some women will begin active labor with Cervidil alone, many will require additional induction methods like Pitocin.

  • Success depends on individual factors: The likelihood of Cervidil alone starting labor is higher for women with a favorable Bishop score or a history of prior vaginal delivery.

  • Hospital monitoring is required: A healthcare professional administers Cervidil in a hospital, and continuous monitoring of the patient and baby is mandatory during its 12-hour release period.

  • It can be easily removed: The vaginal insert includes a retrieval string, allowing for quick removal in the event of complications like uterine tachysystole.

In This Article

What is Cervidil and its primary purpose?

Cervidil is the brand name for dinoprostone, a synthetic prostaglandin, which is a hormone-like substance that occurs naturally in the body. It is administered via a small, flat vaginal insert placed near the cervix by a healthcare professional. Its primary function is called cervical ripening—the process of softening, thinning (effacement), and relaxing the cervix in preparation for labor.

Unlike an IV medication designed to cause contractions, Cervidil works over a period of up to 12 hours, mimicking the natural signals your body uses to prepare for delivery. A healthy induction begins with a cervix that is ready to dilate. If the cervix is not "ripe," induction with a contraction-stimulating drug like Pitocin can be less effective and potentially increase the risk of complications. Therefore, Cervidil is often the first step in a multi-stage induction process, especially for those with an unfavorable cervix, as measured by a Bishop score.

The question of 'Is Cervidil enough to start labor?'

For some women, Cervidil can indeed be enough to initiate strong, regular contractions and kickstart active labor. The success of Cervidil alone is influenced by several factors:

  • Bishop Score: A favorable Bishop score (a measure of cervical dilation, effacement, consistency, and position) prior to induction increases the likelihood of Cervidil being sufficient.
  • Parity: Women who have had previous vaginal deliveries (multiparous) tend to have a higher success rate with Cervidil alone than first-time mothers (nulliparous).
  • Individual Response: Every woman's body responds differently to medication. Some may experience noticeable cramping and contractions, while others only achieve cervical ripening.

For many, however, Cervidil is just the initial step. If strong contractions don't follow after cervical ripening, additional interventions are typically necessary to move the labor process forward.

The next steps: When Cervidil needs a boost

If Cervidil successfully ripens the cervix but doesn't trigger effective contractions, healthcare providers can proceed with other methods. These often include:

  • Oxytocin (Pitocin): This is a synthetic form of the hormone oxytocin, administered intravenously to stimulate uterine contractions. Cervidil is removed at least 30 minutes before starting Pitocin to prevent potential complications from a compounding effect.
  • Amniotomy: This procedure, also known as "breaking the water," involves a healthcare provider using a small hook to rupture the amniotic sac. This can help release natural prostaglandins and speed up contractions.
  • Foley Bulb: A catheter with an inflatable balloon can be inserted into the cervix to apply pressure and encourage dilation mechanically.

Comparing Cervidil with other induction methods

It is important to understand how Cervidil fits into the broader picture of labor induction. Below is a comparison of Cervidil, Pitocin, and the Foley bulb.

Feature Cervidil (Dinoprostone) Pitocin (Oxytocin) Foley Bulb
Primary Function Cervical ripening (softens, thins) Induces/strengthens contractions Mechanical dilation of cervix
Administration Vaginal insert, slow-release over 12 hrs Intravenous (IV) drip, continuous Balloon catheter inserted into cervix
Reversibility Easily removed with retrieval string Drip can be slowed or stopped Balloon can be removed/deflated
Typical Use First step for an unfavorable cervix After cervix is ripe or to strengthen contractions Often combined with prostaglandins or oxytocin
Monitoring Requires monitoring, often for 12 hours Continuous fetal and uterine monitoring Continuous fetal and uterine monitoring
Associated Risk Uterine tachysystole, though often reversible by removal Uterine hyperstimulation, fetal distress Infection, risk of amniotomy

Important considerations and monitoring during Cervidil induction

When Cervidil is administered, it must be done in a hospital setting where continuous monitoring is available. For the first two hours after insertion, the woman must remain lying down. Following this, she may be able to walk around while ensuring the insert remains in place.

The healthcare team will monitor the patient's uterine activity and the baby's heart rate closely for the entire duration the insert is in place. They will watch for signs that labor is progressing or for any adverse effects, such as uterine tachysystole (contractions that are too frequent). If this occurs or if the fetal heart rate shows distress, the insert can be quickly removed to reverse the effect.

Other potential side effects include fever, nausea, vomiting, or diarrhea, but these are often mild and temporary. In rare cases, more serious complications like amniotic fluid embolism or severe bleeding can occur, and patients at higher risk (e.g., age 30+, over 40 weeks gestation) are monitored carefully. Drugs.com provides additional detailed information on Cervidil's uses and warnings.

Conclusion

In summary, while Cervidil's primary role is to ripen a woman's cervix and set the stage for labor, it is not always enough to start labor on its own. For some, particularly those with a favorable Bishop score or prior vaginal delivery, it may trigger contractions and lead directly to delivery. However, for many, it serves as the crucial first step that makes subsequent interventions, like administering Pitocin, more effective and safer. The induction process is highly individualized, and Cervidil's success depends on a combination of maternal factors, cervical readiness, and individual response. Continuous medical monitoring ensures the process is managed safely, regardless of whether Cervidil alone is sufficient.

Frequently Asked Questions

Cervidil contains dinoprostone, a type of prostaglandin that helps ripen the cervix by causing it to soften and thin out. This mimics the natural process your body undergoes before labor, making it more responsive to contractions.

There is no single answer, as it depends on individual factors. The medication is released over 12 hours. For some, labor may start during that time, while others will need additional steps after the Cervidil is removed.

Cervidil is used for cervical ripening, while Pitocin is an IV medication containing synthetic oxytocin used to directly stimulate uterine contractions. Cervidil is often the first step, with Pitocin used afterward if needed.

Yes, Cervidil is not for everyone. Contraindications include a history of previous C-section or major uterine surgery due to the risk of uterine rupture, allergies to prostaglandins, or certain pregnancy complications.

If Cervidil successfully ripens the cervix but contractions are not strong or regular enough, your healthcare provider will likely move to the next phase of induction. This may involve administering Pitocin or an amniotomy.

Common side effects include uterine tachysystole (overly frequent contractions), fever, nausea, vomiting, or diarrhea. Your care team will monitor you closely to manage any adverse reactions.

Yes, Cervidil should be removed once active labor starts, if contractions become too frequent, or after the 12-hour dosage period is complete. The attached retrieval string allows for quick and easy removal.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.