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Is Eliquis cheaper in other countries? A global cost comparison

4 min read

According to Statista, the median monthly price for Eliquis in the U.S. was over five times higher than in Spain or Germany in 2022. This significant price gap raises a crucial question for many American patients: Is Eliquis cheaper in other countries? The answer is a resounding yes, driven by vastly different healthcare pricing systems.

Quick Summary

This article examines the stark price differences for Eliquis (apixaban) between the United States and other nations, explaining the regulatory and market factors contributing to the high U.S. cost. It details potential savings strategies for U.S. patients, including navigating international and domestic options.

Key Points

  • Significant Price Difference: The cost of Eliquis in the U.S. is drastically higher than in Canada, Mexico, and many European countries.

  • Market Factors Drive U.S. Costs: Reasons for the inflated price include a lack of government-negotiated pricing, patent monopolies, and high marketing expenditures.

  • Limited Generic Competition in the U.S.: While the FDA has approved generic apixaban, patent disputes have delayed its market entry in the U.S., unlike other countries where it is available.

  • International Pharmacies Offer Major Savings: Reputable online pharmacies, particularly those in Canada, can provide Eliquis or its generic at a fraction of the U.S. retail price.

  • Domestic Assistance Options Available: U.S. patients can seek help through manufacturer patient assistance programs, co-pay cards, and prescription discount programs to reduce costs.

  • Regulatory Landscape is Evolving: Recent U.S. legislation allows for some government price negotiation, potentially leading to lower costs in the future, though its effects are still unfolding.

In This Article

Understanding the Global Discrepancy in Eliquis Pricing

Eliquis (apixaban) is a critically important anticoagulant used to prevent blood clots. While its medical value is consistent worldwide, its price is not. The cost of this medication in the United States is notoriously high, often representing a significant financial burden for patients. This steep price contrasts sharply with costs observed in other developed nations, where price controls and different healthcare structures keep medication costs much lower.

The Stark Reality of International Eliquis Costs

Comparative data reveals just how dramatic the price difference for Eliquis can be. Reports from sources like Statista and news organizations illustrate the issue clearly. In countries with universal healthcare or robust government price negotiation, the cost is a fraction of the U.S. price. For instance, a 2024 CNN report highlighted the annual list price of Eliquis in the U.S. at $7,100, while in Canada it was $900.

This pricing disparity extends across various regions, with some of the most significant savings found in neighboring countries like Canada and Mexico, and across Europe. The potential for savings can be hundreds or even thousands of dollars annually, prompting many Americans to look for legal and safe ways to access these more affordable international markets.

A Global Eliquis Price Comparison

The following table illustrates a comparative snapshot of Eliquis prices based on recent data. Prices are approximate and can fluctuate, but the overall trend remains consistent.

Location Cost Basis Approximate Monthly Cost (USD) Relative Cost to U.S.
United States Retail (Uninsured) $500 - $600 100%
Canada Pharmacy (Brand Name) $100 - $150 ~20-30%
Mexico Pharmacy (Brand Name) ~$85 (60 tablets) ~15-18%
Germany Median Price (2022) $90 ~18%
Spain Median Price (2022) $96 ~19%
International Online Pharmacy Brand Name/Generic $0.75 per tablet ($45/month) ~9%

Note: The prices for international online pharmacies reflect the cost of generic apixaban, which is not widely available in the U.S. due to patent restrictions.

Why Is Eliquis So Expensive in the U.S.?

Several factors contribute to the vastly inflated cost of Eliquis in the U.S., creating a market environment unlike most others globally.

Reasons for High U.S. Drug Prices:

  • Lack of government negotiation: Unlike many countries where governments negotiate drug prices for the entire population, the U.S. government has historically been prohibited from doing so for Medicare. This allows manufacturers to set their own prices. While recent legislation has begun to change this, the impact is still evolving.
  • Patent Protection: Eliquis is a brand-name drug with strong patent protection, which creates a temporary monopoly for its manufacturers, Bristol Myers Squibb and Pfizer. This exclusivity prevents cheaper generic versions from entering the market, though the FDA has approved some. Patent litigation has further extended this period, with generic availability not expected until at least 2028.
  • Research & Development (R&D) Costs: Pharmaceutical companies cite high R&D costs as a justification for their pricing. However, critics point out that the revenue from drugs like Eliquis far exceeds typical development costs, suggesting pricing is also driven by profit motives.
  • Marketing and Lobbying: Significant spending on marketing to healthcare providers and consumers, as well as extensive lobbying efforts, contribute to maintaining a favorable pricing environment for drug manufacturers in the U.S.

Accessing Affordable Eliquis: Options for American Patients

Despite the challenges, U.S. patients have several avenues to explore for more affordable access to Eliquis or its generic equivalent, apixaban.

  • International Online Pharmacies: Patients can save significantly by ordering from reputable and accredited international online pharmacies. These companies, often based in Canada or other countries with lower drug prices, can provide brand-name Eliquis or generic apixaban at a fraction of the U.S. cost. Patients should only use pharmacies verified by a third-party service like PharmacyChecker.com.
  • Patient Assistance Programs (PAPs): Both the manufacturer, Bristol Myers Squibb, and third-party organizations offer patient assistance programs to help eligible, low-income, and uninsured patients get Eliquis for free or at a reduced cost. These programs often have income and insurance status requirements.
  • Manufacturer Co-pay Cards: For commercially insured patients, the manufacturer offers co-pay cards to reduce out-of-pocket costs. These are not available to patients on government programs like Medicare or Medicaid.
  • Prescription Savings Programs: For uninsured or underinsured patients, discount cards from services like GoodRx can provide some savings, although the final price is still typically much higher than international rates.
  • State Importation Programs: Some U.S. states are exploring or have initiated programs to legally import prescription drugs from Canada. This is a complex process but may offer a long-term solution for broader patient access to lower-cost medication.

Conclusion

For anyone asking, "Is Eliquis cheaper in other countries?", the answer is a definitive yes. The immense cost disparity between the U.S. and other nations is a direct result of differing healthcare systems, regulatory policies, and market dynamics. For American patients, this means facing a substantial financial burden for a necessary medication. While legislative changes and manufacturer programs offer some relief, exploring options through reputable international pharmacies or patient assistance programs remains a critical strategy for managing the high cost of Eliquis. Ultimately, ensuring affordable access requires understanding both the global pricing landscape and the domestic strategies available to navigate it.

For more information on drug pricing policies, you can visit the Peterson-KFF Health System Tracker to compare U.S. costs with other countries.

Frequently Asked Questions

Eliquis is much cheaper in Canada primarily because of the Patented Medicine Prices Review Board (PMPRB), a government agency that regulates the maximum prices for patented medications. The U.S. lacks a similar federal price control mechanism.

While the FDA has regulations regarding importing prescription drugs, many U.S. residents safely use reputable international online pharmacies for personal use. It is crucial to use a pharmacy verified by a service like PharmacyChecker to ensure legitimacy.

While the FDA has approved generic versions of Eliquis, patent litigation has blocked their market entry. The earliest widespread availability of generic apixaban in the U.S. is not expected until at least 2028.

Patient assistance programs (PAPs), often run by manufacturers or charities, provide Eliquis at a free or reduced cost to eligible patients. Eligibility is typically based on income level and insurance status.

The primary factor is the lack of government price negotiation combined with strong patent protection, which gives manufacturers a monopoly and the freedom to set prices higher than in most other countries.

No, co-pay cards offered by manufacturers are not available to patients enrolled in government healthcare programs like Medicare or Medicaid.

Yes, when purchased from accredited pharmacies, the brand-name Eliquis is the same medication, as it is often produced by the same manufacturers, Pfizer and Bristol Myers Squibb. Generic apixaban from accredited sources is also therapeutically equivalent.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.