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Is it safe to be on birth control pills for a long time?

4 min read

According to the Centers for Disease Control and Prevention (CDC), nearly 13% of women in the U.S. using contraception choose birth control pills. For many, this leads to the important question: Is it safe to be on birth control pills for a long time?

Quick Summary

For most healthy women, long-term birth control pill use is considered safe and effective under medical supervision. The balance involves weighing benefits like cancer protection against minor risks like blood clots and potential side effects, depending on individual health factors.

Key Points

  • Long-term use is generally safe: For most healthy women, modern birth control pills are safe for many years under medical supervision.

  • Lowers risk of several cancers: Long-term pill use is associated with a reduced risk of ovarian, endometrial, and colorectal cancers.

  • Slightly increases other cancer risk: There is a small, temporary increase in the risk of breast and cervical cancer for current and recent users, which diminishes over time.

  • Increased cardiovascular risk with estrogen: Combined pills carry a low risk of blood clots, heart attack, and stroke, especially for those over 35 who smoke or have specific health conditions.

  • Fertility is not permanently affected: Long-term pill use does not cause permanent infertility, though it may take a few months for your natural cycle to return after stopping.

  • Individualized risk factors matter: Personal health factors like age, smoking, and family history heavily influence the safety of long-term birth control use.

  • Progestin-only options have different risk profiles: Mini-pills are generally safer regarding cardiovascular risks but require stricter timing and may cause irregular bleeding.

In This Article

The Overall Safety of Extended Birth Control Use

For the majority of healthy women, taking birth control pills for an extended period, even for many years, is considered safe, effective, and a viable long-term contraceptive method. Modern oral contraceptives contain lower doses of hormones than older formulations, which has helped to reduce some associated risks. However, the safety profile is highly individualized and depends on personal medical history, pre-existing conditions, lifestyle choices, and the specific type of pill used. A key component of safe, long-term use is regular medical supervision, with a healthcare provider helping to monitor overall health and adjust the contraception plan as needed.

Health Benefits of Long-Term Oral Contraceptives

Beyond preventing unintended pregnancy, long-term birth control use offers a number of significant non-contraceptive benefits:

  • Reduced cancer risk: Studies have consistently shown that long-term use significantly lowers the risk of developing ovarian, endometrial (uterine lining), and colorectal cancers. This protective effect can last for up to 30 years after stopping the pill.
  • Menstrual cycle regulation: The pill can regulate irregular periods, reduce menstrual cramps (dysmenorrhea), and lead to lighter bleeding. This can prevent or treat anemia caused by heavy bleeding.
  • Symptom management: It is commonly used to treat conditions like endometriosis, polycystic ovary syndrome (PCOS), and premenstrual dysphoric disorder (PMDD), which can cause severe cramps, irregular periods, and mood swings.
  • Acne improvement: The hormonal balance provided by the pill can improve hormonal acne and reduce unwanted hair growth (hirsutism).

Potential Risks of Extended Use

While serious complications are rare, particularly with modern low-dose formulations, there are some potential risks associated with long-term use, especially for certain individuals.

  • Cardiovascular events: Combined birth control pills (containing estrogen) can slightly increase the risk of blood clots (deep vein thrombosis), stroke, and heart attack. The risk is low for most, but is higher in women over 35 who smoke, or those with a history of high blood pressure, migraines with aura, or a blood clotting disorder.
  • Breast and cervical cancer: There is a small, temporary increase in the risk of breast and cervical cancer for current or recent users of hormonal contraceptives. This risk decreases over time after discontinuing the pill and returns to baseline within 5 to 10 years.
  • Minor side effects: Common side effects include breakthrough bleeding or spotting, nausea, breast tenderness, and mood changes, which often subside after the first few months.

Factors Influencing Individual Safety

A healthcare provider will evaluate several factors to determine if long-term pill use is safe for you. These include:

  • Age and smoking status: The combination of being over 35 and smoking significantly increases the risk of serious cardiovascular complications and is a strong contraindication for combined oral contraceptives.
  • Medical and family history: A history of blood clots, stroke, heart attack, migraines with aura, or certain types of cancer in your family can affect your risk profile.
  • Pill formulation: Different pill types carry different risks. Progestin-only pills (mini-pills) are generally safer for those with risks for blood clots and are suitable for breastfeeding women, though they require stricter timing.

Long-Term vs. Short-Term Pill Comparisons

Feature Combined Oral Contraceptives (COCs) Progestin-Only Pills (POPs or Mini-Pill)
Hormones Estrogen and Progestin Progestin only
Primary Mechanism Inhibits ovulation, thickens cervical mucus, thins uterine lining Thicken cervical mucus and thin uterine lining; may not always inhibit ovulation
Required Timing Once a day, more flexible timing window Must be taken at the exact same time each day (within a 3-hour window for most)
Benefits Reduces period cramps, lightens bleeding, improves acne, protects against ovarian/endometrial cancer Safe for smokers over 35, those with high blood pressure, and while breastfeeding
Side Effects Breakthrough bleeding, nausea, breast tenderness, headaches, potential mood changes Irregular bleeding, acne, mood changes, lower libido
Cardiovascular Risk Small but increased risk of blood clots, stroke, and heart attack, especially with risk factors Generally not associated with increased risk of blood clots or stroke

What to Know About Fertility

It is a common myth that long-term use of birth control pills can cause permanent infertility. This is not true. While it may take a few months for your regular menstrual cycle and ovulation to return after stopping, most women's fertility is not affected by long-term pill use. One exception is the Depo-Provera shot, which can cause a longer delay in the return of fertility, sometimes up to a year or more.

Conclusion

Ultimately, whether it is safe to be on birth control pills for a long time depends on a personalized assessment of your health profile by a doctor. For the majority of healthy individuals, the pills are a very safe and effective option with a range of non-contraceptive benefits. The small risks associated with long-term use, especially concerning blood clots and certain cancers, must be weighed against these benefits and a woman's individual health factors. The best approach is to have an open and continuous dialogue with a healthcare provider to ensure your chosen contraceptive method remains the safest and most suitable option for your stage of life. Read more about birth control options at the Mayo Clinic.

Frequently Asked Questions

No, long-term use of most birth control pills does not cause permanent infertility. While it may take a few months for your body's natural cycle to regulate after you stop, your fertility typically returns to your baseline.

No, it is not medically necessary to take a break from birth control pills. There are no recommendations for an upper time limit for oral contraceptive use for most healthy women.

For women who have recently used oral contraceptives, the small, temporary increase in breast cancer risk typically returns to baseline levels within 5 to 10 years after stopping the pill.

The risk of blood clots is primarily associated with combined oral contraceptives (COCs) that contain estrogen. Progestin-only pills (mini-pills) generally do not carry this same risk.

Combined pills use both estrogen and progestin, offering more benefits like acne treatment but carrying a slight cardiovascular risk. Progestin-only pills are safer for those with cardiovascular risks but must be taken at the same time daily and can cause irregular bleeding.

Many healthy women can continue taking the pill after 35, but it is important to discuss it with your doctor. Those over 35 who smoke or have certain risk factors are generally advised against estrogen-containing pills.

After stopping, your body will transition back to its natural hormonal cycle. You may experience temporary side effects like irregular periods, mood changes, or a return of pre-existing symptoms like acne or severe cramps.

Long-term birth control pill use has been shown to reduce the risk of ovarian cancer by 30% to 50%, with this protective effect potentially lasting for many years after you stop using it.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.