Understanding Azelastine and its Role in Allergy Treatment
Azelastine is a second-generation antihistamine used to relieve nasal and ocular symptoms associated with allergies [1.6.2, 1.8.4]. It works by blocking the action of histamine, a chemical your body releases during an allergic reaction that causes symptoms like itching, sneezing, and a runny nose [1.8.1]. Unlike some allergy medications that can take hours or even days to become fully effective, azelastine nasal spray can start working within 15 to 30 minutes [1.9.1]. It is primarily used to treat seasonal allergic rhinitis (hay fever) and perennial (year-round) allergic rhinitis [1.6.1]. Certain formulations can also be used for non-allergic rhinitis (vasomotor rhinitis) and allergic conjunctivitis (itchy eyes from allergies) [1.6.1, 1.6.4].
The Availability of Generic Azelastine
For consumers looking for more affordable options, the good news is that azelastine is widely available as a generic drug [1.2.3]. Generic azelastine hydrochloride is available by prescription in both nasal spray and ophthalmic (eye drop) formulations [1.9.1, 1.10.2]. These generic versions contain the same active ingredient as their brand-name counterparts and are considered just as safe and effective [1.10.2]. Opting for a generic prescription can lead to substantial savings, with some sources reporting prices as low as $5.31 with a coupon, a significant discount off the average retail price [1.4.2]. Generic azelastine is covered by most Medicare and insurance plans [1.2.3].
Brand Names: Astepro, Astelin, and Optivar
Azelastine has been marketed under several brand names:
- Astepro and Astepro Allergy: Astepro is a nasal spray that comes in different strengths. Astepro Allergy (0.15% strength) is now available over-the-counter (OTC), making it the first antihistamine nasal spray to be approved for OTC use in the U.S. [1.2.5, 1.3.5]. The prescription version comes in both 0.1% and 0.15% strengths [1.3.1]. The OTC version features a formula with a sweetener to improve the taste profile compared to older prescription versions [1.3.2].
- Astelin: This was one of the original brand names for prescription azelastine nasal spray (0.1% strength) [1.3.3]. While the brand name Astelin itself may be less common now, its generic equivalent is readily available [1.10.2].
- Optivar: This is the brand name for azelastine eye drops, used to treat itchy eyes from allergic conjunctivitis [1.6.4, 1.10.3]. The brand name Optivar has been discontinued, but the generic azelastine hydrochloride ophthalmic solution is available by prescription [1.10.2, 1.10.5].
Comparison: Generic vs. Brand-Name Azelastine
Choosing between generic and brand-name azelastine often comes down to cost, accessibility, and specific formulation preferences. While OTC Astepro Allergy provides convenience, a prescription for generic azelastine is typically the most budget-friendly choice [1.4.4].
| Feature | Generic Azelastine (Prescription) | Astepro Allergy (OTC) | Astelin (Prescription Brand) |
|---|---|---|---|
| Availability | Prescription required [1.9.1] | Over-the-counter [1.2.5] | Prescription required (Largely replaced by generic) [1.10.2] |
| Strength(s) | 0.1% and 0.15% nasal spray; 0.05% eye drops [1.3.1, 1.10.1] | 0.15% nasal spray [1.3.5] | 0.1% nasal spray [1.3.3] |
| Cost | Generally lowest cost, especially with coupons [1.4.2] | Higher cost than generic prescription [1.4.4] | Highest cost; now largely discontinued in favor of generic [1.10.2] |
| Taste | Can have a notable bitter taste [1.9.1] | Includes a sweetener to mask bitterness [1.9.4] | Known for a bitter taste (20% of users) [1.9.1] |
| Convenience | Requires a doctor's visit/prescription | Can be purchased directly from pharmacies [1.2.5] | Requires a doctor's visit/prescription |
Potential Side Effects and Considerations
Like all medications, azelastine can cause side effects. The most common side effect reported across formulations is a bitter taste in the mouth [1.5.3, 1.9.1]. Other potential side effects include:
- Drowsiness or fatigue [1.5.3]
- Headache [1.5.1]
- Nasal burning or discomfort [1.5.3]
- Nosebleeds [1.5.1]
- Sneezing [1.5.1]
Because azelastine can cause drowsiness, you should be cautious about driving or operating heavy machinery until you know how it affects you [1.5.3]. It is also advised to avoid alcohol, as it can increase this sleepy effect [1.6.1]. Before starting azelastine, inform your doctor of any other medications you are taking [1.5.3].
Conclusion
To answer the question, yes, there is a generic drug for azelastine. Available in both nasal spray and eye drop forms, generic azelastine offers an effective and affordable treatment for allergy symptoms. While the brand Astepro Allergy is conveniently available over-the-counter, a prescription for the generic version is often the most economical path for managing seasonal or year-round allergies. Discussing these options with your healthcare provider can help you determine the best choice for your health needs and budget.
For more information on the mechanism of antihistamines, you can visit MedlinePlus [1.6.2].
