Can I take 100mg of diphenhydramine for sleep?: Risks, Dangers, and Safer Alternatives
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4 min read
According to the American Academy of Sleep Medicine, first-generation antihistamines like diphenhydramine are generally not recommended for either short-term or chronic insomnia due to limited efficacy and safety concerns. Specifically, taking a high dose like 100mg of diphenhydramine for sleep significantly increases the risks of severe side effects, overdose, and developing tolerance.