Tag: Acyclovir side effects

While considered a very safe medication for most people, a systematic review of cases published in the literature found that nearly 74% of neurotoxicity cases linked to antivirals involved acyclovir. This rare but serious side effect can cause confusion, among other neuropsychiatric symptoms, especially in high-risk patients.

Headache is a well-documented side effect of the antiviral medication acyclovir, noted in both clinical practice and studies. For individuals who experience chronic or occasional migraines, this information can be concerning, leading to the question: can acyclovir cause migraines?

Daily suppressive therapy with acyclovir can reduce the subclinical shedding of the herpes simplex virus (HSV) by as much as 94% [1.8.1]. While highly effective, it's important to understand the full spectrum of how does acyclovir make you feel, from common adjustments to rare but serious reactions.