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Tag: Adamts13

Explore our medication guides and pharmacology articles within this category.

Is rituximab FDA approved for TTP? A Review of Its Off-Label Use

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4 min read
Without treatment, thrombotic thrombocytopenic purpura (TTP) has a mortality rate exceeding 90% [1.4.7]. While modern treatments have dramatically improved survival, a key question remains for many: **Is rituximab FDA approved for TTP?** The answer is no, but its role is critical [1.2.1, 1.3.1].

Why rituximab for TTP? Understanding the Pharmacological Approach

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5 min read
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare but life-threatening blood disorder, and the use of rituximab has fundamentally changed its prognosis. Understanding **why rituximab for TTP** is so effective involves delving into its targeted mechanism against the autoimmune cause of the disease.