Does Caffeine Cross the Blood-Brain Barrier? A Pharmacological Review
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4 min read
An estimated 80% to 90% of adults worldwide consume caffeine daily [1.9.2, 1.9.5]. A key question for understanding its widespread effects is: **Does caffeine cross the blood-brain barrier?** The answer is yes, and its ability to do so explains its stimulant properties [1.2.1].