Tag: Adrenal gland

Dexamethasone, a synthetic glucocorticoid, is approximately 30 to 40 times more potent than naturally occurring cortisol [1.2.2, 1.5.4]. Understanding what does dexamethasone do to cortisol is key to its use as both a diagnostic tool and a powerful therapeutic agent.

Dexamethasone is a powerful synthetic corticosteroid that is significantly more potent and longer-acting than the natural hormone it replaces, cortisol. This medication is used extensively in medicine for its strong anti-inflammatory and immunosuppressive effects, often stepping in when the body’s own adrenal glands cannot produce sufficient hormones.

Mitotane, a derivative of the insecticide DDT, has been used since 1959 to treat certain adrenal gland conditions. The antineoplastic agent, also known by the brand name Lysodren, is primarily used for **what is mitotane used for?** The treatment of adrenocortical carcinoma and off-label management of Cushing's syndrome, by controlling excessive hormone production. Its specific mechanism involves both targeted cell destruction and steroid synthesis inhibition within the adrenal cortex.

According to one review, between 5% and 18% of patients using corticosteroids like prednisone can experience psychiatric side effects, including mood elevation or euphoria. If you've been wondering **Why do I feel amazing on prednisone?** you are experiencing a common but complex psychological response to this powerful medication.