Tag: Adrenergic blocker

According to prescribing information, phentolamine is strictly contraindicated in patients with a history of myocardial infarction, coronary insufficiency, or angina. A thorough cardiac evaluation is essential before administration to prevent life-threatening cardiovascular complications.

The antihypertensive medication Guanethidine has been discontinued and is no longer available in the United States for oral use. The drug, once a frontline treatment for severe hypertension, was replaced due to significant side effects and the development of superior medications.