Tag: Aging research

While the idea of a universal anti-aging pill remains science fiction, a 2024 interview with a prominent longevity researcher highlighted several FDA-approved drugs that have shown potential to reduce age-related mortality in humans. The broader scientific conversation often includes four highly-researched compounds: Rapamycin, Metformin, Nicotinamide Mononucleotide (NMN), and Resveratrol, raising the question: **What are the 4 drugs for longevity?**

According to some observational studies, diabetic individuals taking metformin have a reduced risk of age-related diseases, such as cardiovascular disease and certain cancers, potentially lowering all-cause mortality compared to non-diabetics. This has sparked significant interest in its broader effects, prompting the question: **does metformin make you feel younger**?

While preliminary animal and small human studies suggest that nicotinamide mononucleotide (NMN) can boost NAD+ levels to combat age-related decline, the scientific and regulatory landscape is not without significant drawbacks. A critical examination is necessary to fully understand **what are the downsides of NMN?**

In July 2024, NPR reported on a clinical trial testing rapamycin, a generic drug known to extend lifespan in animals, for its potential anti-aging effects in humans. The 'NPR longevity drug' primarily refers to **rapamycin**, though NPR has covered other compounds, such as metformin and senolytics, underscoring the growing field of pharmacological interventions aimed at delaying age-related decline.