Does spironolactone cause ankle swelling? Understanding the medication's effects on edema
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4 min read
Spironolactone is a potassium-sparing diuretic that is often prescribed to reduce fluid retention, or edema, in conditions like heart failure, liver disease, and nephrotic syndrome. However, some people may experience new or worsening fluid buildup in the ankles and feet, raising the question: Does spironolactone cause ankle swelling?. The answer is complex, as swelling while on the medication could be a sign of a new or different issue, not just a side effect.